ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-28.PDB
Scoring matrix: PIN3_1YNZ-28_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.23
Foldx random average score for Saccharomyces cerevisiae: 13.747

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1372727
Proteins after disorder filtering: 4183
 Total fragments: 45316
Proteins after pattern filtering: 1972
 Total fragments: 8413
Proteins after MINT filtering: 22
 Total fragments: 249


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.23

-3.01

0.00

Best peptides

REPIHRRKRK

0.00

-9.24

-6.23

         
Interactors      
Q06604

KPLLPTRPNK

5.96

-11.39

-8.38

FEKGPRMPSR

8.09

-8.95

-5.94

KPTPPSPPAK

9.09

-9.48

-6.47

P24583

NAPLPPQPRK

8.36

-8.81

-5.80

LPPQPRKHDK

8.78

-8.48

-5.47

PLPPQPRKHD

11.16

-8.24

-5.23

P19812

HSPIFRPGNI

11.91

-4.22

-1.21

PRPRRIPPTD

12.18

-6.57

-3.56

PQNPPPILQF

12.49

-6.48

-3.47

P15891

QPPLPSRNVA

8.78

-11.69

-8.68

APPPPPRRAT

9.33

-11.07

-8.06

EAAQPPLPSR

9.49

-7.50

-4.49

Q12344

SPKLPPRGKQ

8.66

-12.27

-9.26

SPPLPPRQNV

10.12

-11.42

-8.41

PPLPPRQNVA

11.56

-8.92

-5.91

P39521

VPDRPPSQLS

11.17

-8.02

-5.01

AQPKPKPAQD

12.24

-5.55

-2.54

PDRPPSQLSA

12.24

-7.56

-4.55

P40325

QPPRPPRPAA

7.59

-11.97

-8.96

QPRPPPRPQQ

8.79

-12.23

-9.22

RPPRPAANLA

9.27

-9.48

-6.47

Q08601

RPMAPPPNQQ

10.47

-8.75

-5.74

PPGPPPMAYN

11.62

-8.69

-5.68

QRPMAPPPNQ

12.23

-7.91

-4.90

Q12168

DDPYFPQFRS

10.02

-5.84

-2.83

DNDDPYFPQF

10.15

-7.31

-4.30

PPPLPPRANV

10.20

-9.64

-6.63

Q12412

YDPNHRPPSS

9.81

-5.32

-2.31

RPPQPPPAYD

9.99

-9.20

-6.19

PPPAYDPNHR

13.43

-8.25

-5.24

Q08412

PPQLPTRTKS

9.42

-10.96

-7.95

EDVPPQLPTR

9.66

-8.18

-5.17

DIELPTQPVR

10.86

-7.33

-4.32

P53118

VENPHDLPSH

10.06

-5.53

-2.52

P38216

RPSNPPPSSA

11.54

-8.32

-5.31

SRPSNPPPSS

13.41

-5.55

-2.54

P53933

RPPPPPIPST

8.69

-9.56

-6.55

RVAPPPLPNR

9.86

-7.46

-4.45

VAPPPLPNRQ

11.69

-7.73

-4.72

Q12446

APPPPPRASR

8.75

-10.85

-7.84

VPPPPPMRTT

8.91

-9.03

-6.02

LPQLPNRNNR

9.04

-11.20

-8.19

P38266

KKKPPVVPKK

7.89

-9.17

-6.16

KKVPPVVPKK

8.23

-8.13

-5.12

PPPKPFRRSQ

8.33

-10.78

-7.77

P40483

KPSVPPRNYF

7.33

-12.18

-9.17

KDAPASKPSV

11.13

-6.58

-3.57

P07244

MPGMYPPGHY

10.15

-10.24

-7.23

EMPGMYPPGH

12.67

-5.17

-2.16

P40563

RRAPPPVPKK

7.60

-10.29

-7.28

PGQLPPSLEK

12.60

-5.78

-2.77

KRRAPPPVPK

12.99

-7.68

-4.67

Q07533

IPPVPSRYSD

7.43

-10.80

-7.79

SDPHFPYGTW

9.98

-7.07

-4.06

VKSDPHFPYG

10.27

-6.55

-3.54

P53901

LPPIPTRDDM

7.79

-11.40

-8.39

MRPIPPLPTE

8.25

-7.71

-4.70

QPPLPPIPTR

9.93

-9.75

-6.74

Q12489

RPSAPPPGYE

12.42

-8.71

-5.70

 


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