ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-19.PDB
Scoring matrix: PIN3_1YNZ-19_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.51
Foldx random average score for Saccharomyces cerevisiae: 14.683

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1493042
Proteins after disorder filtering: 4580
 Total fragments: 79278
Proteins after pattern filtering: 2131
 Total fragments: 9169
Proteins after MINT filtering: 22
 Total fragments: 214


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.51

-2.37

0.00

Best peptides

FPFMFGRHL

0.00

-5.22

-2.85

         
Interactors      
Q06604

GPRMPSRGR

10.11

-7.34

-4.97

PPSPPAKRI

10.39

-8.61

-6.24

KPTPPSPPA

11.75

-6.99

-4.62

P40325

RPPRPAANL

8.20

-10.41

-8.04

LYVQPGDPR

12.06

-3.82

-1.45

PPPRPQQNP

12.29

-7.56

-5.19

Q04322

DQAPLDRPQ

12.34

-4.32

-1.95

NDQAPLDRP

13.59

-5.85

-3.48

Q12168

PPLPPRANV

10.75

-7.84

-5.47

VPNRPGGTT

11.42

-5.71

-3.34

RGPPPLPPR

11.78

-7.07

-4.70

P15891

RRATPEKKP

11.38

-4.85

-2.48

RATPEKKPK

12.72

-4.83

-2.46

QPPLPSRNV

12.95

-7.25

-4.88

Q12344

PPLPPRQNV

10.97

-8.27

-5.90

PKLPPRGKQ

11.44

-6.62

-4.25

STSPKLPPR

13.39

-4.89

-2.52

P39521

VDAQPKPKP

13.43

-6.18

-3.81

PDRPPSQLS

13.91

-5.50

-3.13

P24583

LPPQPRKHD

10.68

-7.67

-5.30

APLPPQPRK

10.81

-7.56

-5.19

PPQPRKHDK

12.19

-6.37

-4.00

Q08601

YAPPPGPPP

13.23

-7.29

-4.92

YQRPMAPPP

14.09

-6.50

-4.13

PGPPPMAYN

14.28

-5.48

-3.11

P19812

PIFRPGNIF

10.69

-8.18

-5.81

EPRPRRIPP

12.80

-7.93

-5.56

DHSPIFRPG

13.13

-4.16

-1.79

Q12412

AYDPNHRPP

12.56

-5.14

-2.77

PPPAYDPNH

13.23

-6.96

-4.59

PAYDPNHRP

13.81

-5.36

-2.99

Q08412

LPTQPVRKN

12.57

-6.61

-4.24

QPLPPEPLD

12.78

-7.66

-5.29

DVPPQLPTR

12.84

-5.34

-2.97

P53118

SVENPHDLP

14.26

-6.43

-4.06

P53933

PPLPNRQLP

11.79

-7.54

-5.17

VAPPPLPNR

11.80

-5.78

-3.41

NDLPMELPH

12.48

-4.17

-1.80

Q12446

PPPPPHRHV

8.38

-9.71

-7.34

RPLPQLPNR

8.57

-6.79

-4.42

LPDPPQHNS

10.79

-6.55

-4.18

P38266

PPKPFRHGL

9.32

-7.44

-5.07

PPPKPFRHG

9.77

-7.71

-5.34

PPLKPGQKT

9.79

-6.68

-4.31

P40483

PSVPPRNYF

13.32

-6.67

-4.30

TKDAPASKP

13.49

-5.48

-3.11

P07244

TSEMPGMYP

10.35

-5.83

-3.46

P40563

GMVNPGQLP

11.88

-6.86

-4.49

PSERPKRRA

12.32

-7.90

-5.53

PPTPAGTPN

12.46

-6.06

-3.69

Q07533

NPLPPLPPL

9.99

-8.91

-6.54

PHFPYGTWK

11.36

-6.56

-4.19

PPLPPLPDL

11.39

-7.55

-5.18

P53901

RPIPPLPTE

10.81

-7.50

-5.13

DSSSPNSHP

11.73

-5.58

-3.21

LNSPKLPPL

12.44

-6.11

-3.74

P37254

GPGPGNPNN

13.85

-5.61

-3.24

PGNPNNGAQ

14.53

-3.32

-0.95

 


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