ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-16.PDB
Scoring matrix: PIN3_1YNZ-16_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.6
Foldx random average score for Saccharomyces cerevisiae: 15.106

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1568290
Proteins after disorder filtering: 4656
 Total fragments: 106166
Proteins after pattern filtering: 2226
 Total fragments: 12440
Proteins after MINT filtering: 24
 Total fragments: 335


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.60

0.88

0.00

Best peptides

RHPIRSIWR

0.00

0.31

-0.56

         
Interactors      
Q06604

YSNIPSSKP

9.68

-1.80

-2.67

LLPTRPNKA

10.02

-2.43

-3.31

GPRMPSRGR

10.93

-3.78

-4.65

P24583

LPPQPRKHD

11.65

-2.32

-3.19

NAPLPPQPR

11.79

-2.67

-3.54

Q04322

TPPTLPPRR

10.49

-3.10

-3.98

TPSKSPTSA

11.57

-3.06

-3.94

GNATPSKSP

12.49

0.70

-0.18

Q12168

PPPLPPRAN

12.05

-2.65

-3.52

PPPVPNRPG

13.06

-3.23

-4.11

IPPPVPNRP

13.06

-6.60

-7.47

P15891

KSFTPSKSP

9.53

-1.95

-2.83

RRATPEKKP

9.94

-1.10

-1.98

KEPVKTPSP

10.16

-0.61

-1.48

Q12344

SPPLPPRQN

11.23

-4.59

-5.46

TSPKLPPRG

12.43

-2.40

-3.27

SPKLPPRGK

14.62

-4.46

-5.34

P39521

VDAQPKPKP

11.80

-4.28

-5.16

TPHVPDRPP

12.94

-2.32

-3.19

PKPKPAQDN

14.55

2.30

1.42

P40325

RPHQRPSTM

8.66

-4.90

-5.78

NPSLPWTYP

9.56

-4.84

-5.71

RPQQNPSLP

9.72

-4.13

-5.00

Q08601

MAYNRPVYP

11.81

-2.15

-3.02

RPMAPPPNQ

11.92

-2.66

-3.54

NGYQRPMAP

12.73

-0.58

-1.46

P19812

RPRRIPPTD

10.36

-4.51

-5.38

AKTSPSNSP

12.57

0.00

-0.88

PIFRPGNIF

12.85

-0.93

-1.81

Q12412

RPPQPPPAY

8.42

-4.12

-5.00

PPAYDPNHR

11.92

-1.97

-2.84

DPNHRPPSS

12.23

-1.57

-2.45

Q08412

KDIELPTQP

11.57

-1.65

-2.52

KKKWQPLPP

11.70

-1.75

-2.63

KNSRPQQPE

12.07

-1.24

-2.12

P53118

PHDLPSHLG

8.59

-2.39

-3.27

ENPHDLPSH

14.88

-0.34

-1.22

SVENPHDLP

15.09

-0.93

-1.81

P38216

RPSNPPPSS

8.85

-3.43

-4.30

QYSRPSNPP

12.39

-2.09

-2.96

SQYSRPSNP

13.51

-0.39

-1.27

P53933

RTRRRPPPP

11.12

-4.63

-5.50

YNDLPMELP

11.38

-3.17

-4.04

RPPPPPIPS

11.66

-3.24

-4.12

Q12446

LPPLPNQFA

8.83

-4.84

-5.71

IPEIPSTQS

8.94

-3.88

-4.75

KHSLPPLPN

9.35

-1.32

-2.20

P38266

RNVEPSLVP

8.78

-3.66

-4.54

TPPRPPPSR

10.12

-4.03

-4.91

PPPKPFRHG

10.20

-3.23

-4.11

P40483

KPSVPPRNY

8.03

-4.36

-5.24

APASKPSVP

12.89

-1.20

-2.08

KDAPASKPS

13.91

0.74

-0.14

P07244

TSEMPGMYP

10.95

-1.92

-2.79

MPGMYPPGH

13.54

-4.56

-5.43

PGMYPPGHY

14.78

-2.56

-3.44

P40563

PSERPKRRA

11.92

-1.22

-2.09

GMVNPGQLP

12.55

-2.19

-3.06

KRRAPPPVP

12.61

-2.66

-3.54

Q07533

IPPVPSRYS

8.11

-2.83

-3.71

LPPLPDLDN

10.91

-4.15

-5.03

NNPLPPLPP

11.83

-2.59

-3.46

P53901

DPIILPPTF

11.27

-4.03

-4.91

IPPLPTESE

11.28

-3.66

-4.54

RPIPPLPTE

11.42

-1.88

-2.75

P37254

GPGNPNNGA

14.21

-0.74

-1.62

Q12489

RPSAPPPGY

11.54

-3.28

-4.15

SYSRPSAPP

13.16

-1.02

-1.90

QSYSRPSAP

14.59

-1.76

-2.63

 


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