ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-15.PDB
Scoring matrix: PIN3_1YNZ-15_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.78
Foldx random average score for Saccharomyces cerevisiae: 13.472

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1344912
Proteins after disorder filtering: 3860
 Total fragments: 36174
Proteins after pattern filtering: 1470
 Total fragments: 4032
Proteins after MINT filtering: 21
 Total fragments: 129


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

18.78

-0.38

0.00

Best peptides

RPFMIRKRR

0.00

-9.60

-9.22

         
Interactors      
P39521

AQPKPKPAQ

12.62

-2.80

-2.42

Q06604

PLLPTRPNK

10.61

-5.00

-4.62

GPRMPSRGR

11.52

-8.70

-8.32

LLPTRPNKA

11.91

-4.55

-4.17

P38216

RPSNPPPSS

12.79

-4.62

-4.24

P24583

LPPQPRKHD

9.63

-7.55

-7.17

PPQPRKHDK

12.09

-3.57

-3.19

APLPPQPRK

12.12

-5.22

-4.84

P07244

MPGMYPPGH

12.85

-5.10

-4.72

P53933

PPPIPSTQK

12.80

-5.58

-5.20

RRRPPPPPI

13.08

-5.79

-5.41

Q08601

RPMAPPPNQ

12.30

-5.18

-4.80

P53901

PPIPTRDDM

10.31

-5.87

-5.49

RPIPPLPTE

11.73

-6.04

-5.66

PPLPPIPTR

12.73

-4.27

-3.89

Q12168

QHPVPKPNI

10.09

-5.08

-4.70

PPLPPRANV

11.77

-6.17

-5.79

RGPPPLPPR

13.17

-5.60

-5.22

P40325

RPHQRPSTM

8.43

-6.12

-5.74

SRPHQRPST

9.59

-5.25

-4.87

RPSTMPATS

10.32

-4.80

-4.42

Q07533

KSPKAYPKL

11.11

-5.75

-5.37

MPNSPKKPV

12.43

-4.44

-4.06

PPVPSRYSD

13.20

-5.21

-4.83

P15891

RRATPEKKP

11.36

-4.95

-4.57

RATPEKKPK

11.55

-2.46

-2.08

PPLPSRNVA

11.86

-4.91

-4.53

P40563

RAPPPVPKK

11.31

-4.51

-4.13

PSERPKRRA

12.51

-4.98

-4.60

RRAPPPVPK

12.76

-5.16

-4.78

Q12446

RPLPQLPNR

9.12

-4.84

-4.46

PPPPPRASR

10.11

-7.01

-6.63

PPPPMRTTT

10.87

-6.34

-5.96

P19812

HSPIFRPGN

10.37

-5.61

-5.23

RPRRIPPTD

10.62

-7.38

-7.00

SPIFRPGNI

12.45

-4.92

-4.54

Q08412

ELPTQPVRK

10.13

-3.40

-3.02

LPPEPLDTT

11.95

-5.34

-4.96

VPPQLPTRT

11.99

-5.06

-4.68

Q12344

PKLPPRGKQ

11.71

-5.99

-5.61

PPLPPRQNV

11.93

-7.44

-7.06

SPKLPPRGK

12.63

-5.13

-4.75

Q12412

RPPQPPPAY

12.42

-4.66

-4.28

PPAYDPNHR

13.17

-7.00

-6.62

YDPNHRPPS

13.47

-5.03

-4.65

P38266

KPPVVPKKK

7.49

-6.62

-6.24

PPPKPFRRS

9.86

-6.21

-5.83

FLPPPKPFR

10.08

-5.27

-4.89

P40483

KPSVPPRNY

12.74

-5.50

-5.12

Q04322

TPPTLPPRR

9.61

-8.14

-7.76

PPTLPPRRI

11.31

-7.15

-6.77

QAPLDRPQL

12.96

-5.13

-4.75

 


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