ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-13.PDB
Scoring matrix: PIN3_1YNZ-13_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.55
Foldx random average score for Saccharomyces cerevisiae: 14.403

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7178
 Total fragments: 1585763
Proteins after disorder filtering: 4804
 Total fragments: 118180
Proteins after pattern filtering: 2308
 Total fragments: 15833
Proteins after MINT filtering: 25
 Total fragments: 437


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.55

1.44

0.00

Best peptides

RHPMGNWW

0.00

-3.85

-5.29

         
Interactors      
Q06604

PPPLPTRR

6.16

-7.85

-9.29

KPLLPTRP

6.57

-8.82

-10.26

LPTRPNKA

6.66

-6.55

-7.99

P24583

LPPQPRKH

7.54

-6.75

-8.19

NAPLPPQP

10.42

-3.71

-5.15

APLPPQPR

10.65

-2.90

-4.34

P38260

GPDDPTLM

8.03

-5.55

-6.99

Q04322

PPTLPPRR

5.90

-8.08

-9.52

SPPLPPRA

7.98

-7.94

-9.38

PTLPPRRI

10.19

-5.85

-7.29

Q12168

PPPVPNRP

7.34

-7.73

-9.17

PPPLPPRA

8.03

-8.13

-9.57

DPYFPQFR

8.18

-4.89

-6.33

P15891

APPPPPRR

6.49

-7.44

-8.88

QPPLPSRN

7.61

-8.45

-9.89

PPPPPRRA

9.41

-7.22

-8.66

Q12344

SPPLPPRQ

7.93

-8.03

-9.47

SPKLPPRG

8.39

-8.37

-9.81

TTSSPPLP

10.01

-5.59

-7.03

P39521

TPHVPDRP

9.19

-7.35

-8.79

VPDRPPSQ

10.69

-3.87

-5.31

PKPKPAQD

11.45

-3.36

-4.80

P40325

QPPRPPRP

6.61

-8.08

-9.52

QPGDPRLG

7.74

-6.05

-7.49

RPPRPAAN

7.87

-5.56

-7.00

Q08601

RPMAPPPN

9.50

-5.19

-6.63

AYNRPVYP

9.66

-4.90

-6.34

PPGPPPMA

10.13

-5.05

-6.49

P19812

PIFRPGNI

10.31

-5.33

-6.77

PRRIPPTD

10.95

-4.61

-6.05

PEASPSLA

11.17

-4.16

-5.60

Q12412

PAYDPNHR

8.11

-3.66

-5.10

RPPQPPPA

8.34

-4.93

-6.37

AYDPNHRP

10.72

-5.09

-6.53

Q08412

LPTQPVRK

7.02

-8.25

-9.69

PPQLPTRT

8.96

-7.65

-9.09

KNSRPQQP

9.10

-4.31

-5.75

P53118

PHDLPSHL

10.16

-2.96

-4.40

VENPHDLP

11.75

-1.76

-3.20

NPHDLPSH

12.98

-2.83

-4.27

P38216

RPSNPPPS

8.89

-6.11

-7.55

QYSRPSNP

10.44

-4.10

-5.54

SRPSNPPP

12.47

-2.55

-3.99

P53933

RPPPPPIP

6.66

-7.14

-8.58

RVAPPPLP

6.73

-6.48

-7.92

PPPLPNRQ

7.47

-8.03

-9.47

Q12446

KHSLPPLP

5.86

-6.59

-8.03

LPQLPNRN

6.42

-8.62

-10.06

APPPPPRR

6.49

-7.44

-8.88

P38266

PPPKPFRR

5.73

-7.87

-9.31

LPPPPTHR

7.52

-5.33

-6.77

QPPVPVRM

7.61

-8.02

-9.46

P40483

KPSVPPRN

6.47

-8.45

-9.89

KDAPASKP

11.28

-3.12

-4.56

PASKPSVP

11.71

-3.13

-4.57

P07244

SEMPGMYP

10.78

-3.46

-4.90

MPGMYPPG

13.61

-4.37

-5.81

P40563

PSERPKRR

7.77

-5.89

-7.33

MVNPGQLP

8.30

-5.86

-7.30

RRAPPPVP

8.35

-3.84

-5.28

Q07533

LPPLPPLP

6.48

-7.72

-9.16

IPPVPSRY

6.89

-8.34

-9.78

NNPLPPLP

7.39

-4.88

-6.32

P53901

MRPIPPLP

5.69

-8.08

-9.52

LPPIPTRD

6.54

-9.21

-10.65

QPPLPPIP

7.79

-6.90

-8.34

P37254

GPGNPNNG

10.98

-3.83

-5.27

GPGPGNPN

11.41

-2.23

-3.67

VGPGPGNP

13.97

-1.21

-2.65

Q12489

RPSAPPPG

9.69

-5.24

-6.68

SYSRPSAP

11.49

-3.62

-5.06

SRPSAPPP

13.36

-2.14

-3.58

 


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