ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-11.PDB
Scoring matrix: PIN3_1YNZ-11_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.11
Foldx random average score for Saccharomyces cerevisiae: 10.057

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1410061
Proteins after disorder filtering: 4844
 Total fragments: 117797
Proteins after pattern filtering: 2305
 Total fragments: 14206
Proteins after MINT filtering: 26
 Total fragments: 404


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

12.11

0.93

0.00

Best peptides

RRPIFRY

0.00

-3.05

-3.98

         
Interactors      
Q06604

KPLLPTR

5.17

-3.93

-4.86

GPRMPSR

5.54

-3.90

-4.83

KPTPPSP

6.01

-3.43

-4.36

P24583

LPPQPRK

5.23

-4.51

-5.44

APLPPQP

7.22

-3.19

-4.12

PLPPQPR

8.50

-2.08

-3.01

P38260

GPDDPTL

8.70

-2.04

-2.97

PDDPTLM

9.54

-0.51

-1.44

Q04322

SPPLPPR

6.43

-3.76

-4.69

PPTLPPR

6.81

-5.30

-6.23

PTLPPRR

6.82

-3.21

-4.14

Q12168

DPYFPQF

4.68

-2.83

-3.76

PPPVPNR

5.43

-4.51

-5.44

PPPLPPR

6.27

-4.57

-5.50

P15891

PPPPPRR

5.08

-3.97

-4.90

APPPPPR

5.86

-5.49

-6.42

KTPSPAP

6.59

-0.19

-1.12

Q12344

SPPLPPR

6.43

-3.76

-4.69

SPKLPPR

6.67

-3.50

-4.43

PPLPPRQ

7.06

-2.94

-3.87

P39521

TPHVPDR

6.22

-3.00

-3.93

VPDRPPS

7.52

-3.11

-4.04

AQPKPKP

8.02

-2.13

-3.06

P40325

RPPRPAA

4.94

-4.83

-5.76

QPPRPPR

5.61

-4.60

-5.53

PRPPPRP

5.95

-3.46

-4.39

Q08601

RPVYPPP

4.93

-4.73

-5.66

RPMAPPP

5.45

-4.22

-5.15

NRPVYPP

5.83

-0.97

-1.90

Q12532

PFKPYIN

9.82

0.73

-0.20

P19812

PRRIPPT

6.50

-3.04

-3.97

HSPIFRP

6.87

-2.77

-3.70

APQNPPP

7.02

-3.73

-4.66

Q12412

RPPQPPP

3.76

-5.29

-6.22

YDPNHRP

5.38

-3.57

-4.50

PQPPPAY

7.26

-2.32

-3.25

Q08412

LPTQPVR

5.76

-4.34

-5.27

PPQLPTR

7.28

-4.55

-5.48

SRPQQPE

8.67

-0.64

-1.57

P53118

PHDLPSH

9.44

-1.27

-2.20

P38216

RPSNPPP

4.27

-5.17

-6.10

SRPSNPP

8.15

-1.10

-2.03

YSRPSNP

9.38

-1.99

-2.92

P53933

RRPPPPP

4.14

-4.45

-5.38

RRRPPPP

4.42

-3.78

-4.71

RPPPPPI

4.86

-4.67

-5.60

Q12446

PPPPPRR

5.08

-3.97

-4.90

NRPVPPP

5.25

-2.40

-3.33

RPVPPPP

5.32

-4.74

-5.67

P38266

PPKPFRR

5.13

-3.80

-4.73

FPPPPLK

5.15

-4.66

-5.59

PPPKPFR

5.45

-4.40

-5.33

P40483

KPSVPPR

3.78

-5.31

-6.24

PASKPSV

9.28

-1.33

-2.26

APASKPS

9.30

-1.03

-1.96

P07244

MPGMYPP

6.31

-3.40

-4.33

P40563

TPNVPTR

6.42

-3.09

-4.02

RAPPPVP

6.58

-2.27

-3.20

PPPVPKK

6.67

-5.00

-5.93

Q07533

IPPVPSR

4.69

-3.98

-4.91

SDPHFPY

6.14

-2.05

-2.98

MPNSPKK

6.33

-3.26

-4.19

P53901

LPPIPTR

5.02

-6.00

-6.93

MRPIPPL

5.04

-3.60

-4.53

RPIPPLP

5.20

-3.61

-4.54

P37254

GPGPGNP

8.38

-2.35

-3.28

GPGNPNN

8.43

-2.48

-3.41

Q12489

RPSAPPP

5.25

-4.83

-5.76

SRPSAPP

8.10

-2.06

-2.99

YSRPSAP

9.63

-1.42

-2.35

 


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