ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-9.PDB
Scoring matrix: PIN3_1CKB-9_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.0
Foldx random average score for Saccharomyces cerevisiae: 14.057

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1419478
Proteins after disorder filtering: 4535
 Total fragments: 72362
Proteins after pattern filtering: 2273
 Total fragments: 14258
Proteins after MINT filtering: 25
 Total fragments: 398


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.00

-3.00

0.00

Best peptides

RPFRPPFW

0.00

-7.67

-4.67

         
Interactors      
Q06604

LPTRPNKA

6.66

-7.36

-4.36

KPLLPTRP

7.50

-11.11

-8.11

NEEKPLLP

8.67

-6.76

-3.76

P24583

LPPQPRKH

7.68

-8.81

-5.81

RANAPLPP

10.56

-7.23

-4.23

NAPLPPQP

11.03

-7.70

-4.70

P38260

GPDDPTLM

11.34

-6.96

-3.96

Q04322

SPPLPPRA

9.51

-8.29

-5.29

PPTLPPRR

9.53

-8.36

-5.36

TPSKSPTS

12.28

-3.71

-0.71

Q12168

PPPVPNRP

8.31

-9.31

-6.31

PPPLPPRA

8.90

-9.30

-6.30

DPYFPQFR

9.41

-7.36

-4.36

P15891

KPEVPEDE

8.16

-6.50

-3.50

QPPLPSRN

9.01

-9.30

-6.30

APPPPPRR

9.94

-7.58

-4.58

Q12344

SPPLPPRQ

10.10

-8.40

-5.40

SPKLPPRG

10.45

-8.40

-5.40

PPLPPRQN

12.00

-6.09

-3.09

P39521

TPHVPDRP

8.00

-8.21

-5.21

VPDRPPSQ

9.38

-6.61

-3.61

PKPKPAQD

9.90

-5.74

-2.74

P40325

RPPRPAAN

5.23

-9.29

-6.29

QPPRPPRP

6.14

-9.18

-6.18

NPSLPWTY

8.30

-8.75

-5.75

Q08601

RPMAPPPN

7.96

-8.31

-5.31

AYNRPVYP

9.38

-6.91

-3.91

PPGPPPMA

10.49

-7.15

-4.15

P19812

RPRRIPPT

8.80

-9.10

-6.10

PRRIPPTD

9.49

-6.68

-3.68

PIFRPGNI

10.16

-5.98

-2.98

Q12412

RPPQPPPA

6.25

-8.83

-5.83

PNHRPPSS

10.37

-5.09

-2.09

PPQPPPAY

10.94

-6.48

-3.48

Q08412

KNSRPQQP

7.84

-8.64

-5.64

LPTQPVRK

8.09

-8.46

-5.46

KKWQPLPP

8.31

-6.05

-3.05

P53118

PHDLPSHL

12.44

-6.33

-3.33

NPHDLPSH

13.19

-5.08

-2.08

P38216

RPSNPPPS

6.96

-7.78

-4.78

QYSRPSNP

10.58

-6.39

-3.39

P53933

RPPPPPIP

6.72

-9.34

-6.34

RRPPPPPI

7.77

-7.90

-4.90

RRRPPPPP

7.88

-9.56

-6.56

Q12446

RNNRPVPP

6.63

-7.36

-4.36

RPVPPPPP

7.53

-8.25

-5.25

LPPLPNQF

7.63

-9.75

-6.75

P38266

QPPVPVRM

6.82

-9.01

-6.01

TPPRPPPS

8.08

-7.18

-4.18

FPPPPLKP

8.22

-9.09

-6.09

P40483

KPSVPPRN

6.03

-8.19

-5.19

KDAPASKP

12.05

-5.11

-2.11

PASKPSVP

12.15

-5.16

-2.16

P07244

MPGMYPPG

11.31

-7.37

-4.37

P40563

RRAPPPVP

7.75

-7.67

-4.67

PPPVPKKP

7.94

-9.66

-6.66

TPKVPERP

8.28

-10.49

-7.49

Q07533

IPPVPSRY

5.19

-10.42

-7.42

LPPLPPLP

7.68

-10.78

-7.78

LPPLPDLD

8.53

-10.16

-7.16

P53901

MRPIPPLP

6.36

-9.75

-6.75

LPPIPTRD

6.53

-9.80

-6.80

RPIPPLPT

8.17

-6.85

-3.85

P37254

GPGNPNNG

12.69

-4.41

-1.41

Q12489

RPSAPPPG

8.03

-8.55

-5.55

SYSRPSAP

11.85

-5.56

-2.56

PSAPPPGY

12.58

-5.14

-2.14

 


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