ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-29.PDB
Scoring matrix: PIN3_1CKB-29_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.77
Foldx random average score for Saccharomyces cerevisiae: 16.270

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1472644
Proteins after disorder filtering: 4180
 Total fragments: 53415
Proteins after pattern filtering: 2135
 Total fragments: 13182
Proteins after MINT filtering: 24
 Total fragments: 408


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.77

-0.55

0.00

Best peptides

RLPWYPKRMH

0.00

-8.67

-8.12

         
Interactors      
Q06604

EKPLLPTRPN

5.45

-11.53

-10.98

SPPPLPTRRD

7.03

-10.76

-10.21

KGPRMPSRGR

8.66

-10.27

-9.72

P24583

PLPPQPRKHD

8.61

-8.35

-7.80

APLPPQPRKH

10.95

-8.60

-8.05

LPPQPRKHDK

13.53

-7.92

-7.37

Q04322

TPPTLPPRRI

6.52

-10.60

-10.05

TSPPLPPRAD

6.86

-9.96

-9.41

STPPTLPPRR

13.50

-7.44

-6.89

P19812

HSPIFRPGNI

12.09

-4.00

-3.45

PQNPPPILQF

12.33

-6.21

-5.66

DAPQNPPPIL

13.35

-6.98

-6.43

P15891

AQPPLPSRNV

5.53

-10.64

-10.09

APPPPPRRAT

9.76

-9.68

-9.13

AAPPPPPRRA

9.86

-8.55

-8.00

Q12344

SSPPLPPRQN

6.27

-11.14

-10.59

TSPKLPPRGK

7.18

-10.05

-9.50

PKLPPRGKQR

11.87

-7.03

-6.48

P39521

QTPHVPDRPP

7.83

-8.81

-8.26

HVPDRPPSQL

13.64

-7.91

-7.36

QPKPKPAQDN

14.59

-6.99

-6.44

P40325

SQPPRPPRPA

6.05

-11.38

-10.83

SQPRPPPRPQ

7.28

-10.48

-9.93

LPWTYPPRFY

7.33

-7.98

-7.43

Q08601

PPPGPPPMAY

12.51

-8.30

-7.75

APPPGPPPMA

12.90

-9.19

-8.64

QRPMAPPPNQ

13.30

-6.39

-5.84

Q12532

PFKPYINGGD

15.48

-6.28

-5.73

Q12168

IPPPVPNRPG

6.88

-9.84

-9.29

GPPPLPPRAN

6.97

-10.83

-10.28

DDPYFPQFRS

10.06

-9.32

-8.77

Q12412

PAYDPNHRPP

13.35

-5.06

-4.51

PPPAYDPNHR

13.76

-6.88

-6.33

RPPQPPPAYD

14.98

-6.74

-6.19

Q08412

ELPTQPVRKN

6.45

-9.25

-8.70

VPPQLPTRTK

7.90

-10.34

-9.79

TKKKWQPLPP

11.15

-7.13

-6.58

P53118

NPHDLPSHLG

12.49

-10.61

-10.06

SVENPHDLPS

13.57

-6.09

-5.54

PHDLPSHLGS

15.41

-2.59

-2.04

P38216

SRPSNPPPSS

14.29

-6.40

-5.85

SQYSRPSNPP

15.60

-7.91

-7.36

P53933

APPPLPNRQL

7.04

-11.58

-11.03

PPLPNRQLPN

10.37

-7.38

-6.83

RRPPPPPIPS

11.80

-10.18

-9.63

Q12446

PLPQLPNRNN

5.79

-11.54

-10.99

SLPPLPNQFA

8.61

-10.22

-9.67

PKHSLPPLPN

9.08

-9.19

-8.64

P38266

GQPPVPVRMQ

3.64

-12.22

-11.67

AVPILPPRNN

5.48

-10.85

-10.30

LPPPKPFRHT

7.53

-7.91

-7.36

P40483

SKPSVPPRNY

6.22

-9.84

-9.29

TKDAPASKPS

15.56

-3.53

-2.98

P07244

EMPGMYPPGH

12.52

-9.52

-8.97

MPGMYPPGHY

13.64

-5.15

-4.60

ETSEMPGMYP

14.62

-7.68

-7.13

P40563

APPPVPKKPS

8.29

-8.90

-8.35

RAPPPVPKKP

12.68

-7.50

-6.95

PSERPKRRAP

13.71

-5.78

-5.23

Q07533

PLPPLPPLPD

5.08

-11.58

-11.03

PLPPLPDLDN

6.96

-9.78

-9.23

SMPNSPKKPV

9.50

-7.54

-6.99

P53901

PLPPIPTRDD

6.12

-11.98

-11.43

NSPKLPPLPT

6.84

-9.33

-8.78

AMRPIPPLPT

8.02

-11.26

-10.71

Q12489

SRPSAPPPGY

14.72

-6.60

-6.05

 


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