ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-13.PDB
Scoring matrix: PIN3_1CKB-13_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 13.94
Foldx random average score for Saccharomyces cerevisiae: 12.855

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1427041
Proteins after disorder filtering: 4775
 Total fragments: 103334
Proteins after pattern filtering: 2297
 Total fragments: 15742
Proteins after MINT filtering: 25
 Total fragments: 430


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

13.94

-2.50

0.00

Best peptides

MPFLHPWF

0.00

-4.83

-2.34

         
Interactors      
Q06604

LPTRPNKA

7.16

-6.90

-4.41

GPRMPSRG

7.90

-8.28

-5.78

KPLLPTRP

8.13

-7.98

-5.49

P24583

NAPLPPQP

6.65

-6.67

-4.17

LPPQPRKH

7.21

-7.04

-4.54

APLPPQPR

11.44

-5.56

-3.06

P38260

GPDDPTLM

7.96

-6.63

-4.13

Q04322

SPPLPPRA

7.03

-8.51

-6.01

PPTLPPRR

8.32

-9.06

-6.57

PPLPPRAD

9.41

-5.70

-3.21

Q12168

PPPLPPRA

6.67

-8.44

-5.94

PVPKPNID

7.43

-5.54

-3.04

NRGPPPLP

8.63

-6.26

-3.76

P15891

QPPLPSRN

7.37

-8.01

-5.51

EAAQPPLP

9.38

-6.65

-4.16

PPPPPRRA

9.42

-5.57

-3.08

Q12344

SPKLPPRG

7.03

-8.73

-6.24

PPLPPRQN

7.61

-6.36

-3.87

SPPLPPRQ

8.36

-8.74

-6.25

P39521

PKPKPAQD

8.27

-5.63

-3.13

VPDRPPSQ

9.55

-5.94

-3.45

AQPKPKPA

9.91

-4.82

-2.33

P40325

RPPRPAAN

7.18

-7.24

-4.75

QPGDPRLG

7.30

-6.71

-4.21

PPPRPQQN

7.37

-6.26

-3.76

Q08601

RPMAPPPN

7.92

-7.28

-4.79

PPGPPPMA

8.28

-8.11

-5.61

AYNRPVYP

9.46

-5.57

-3.08

P19812

PRRIPPTD

9.22

-4.92

-2.42

PEASPSLA

9.81

-5.48

-2.99

APQNPPPI

10.20

-5.35

-2.85

Q12412

RPPQPPPA

6.71

-8.20

-5.70

YDPNHRPP

9.22

-1.32

1.18

PNHRPPSS

9.24

-3.45

-0.96

Q08412

DIELPTQP

7.51

-7.09

-4.59

KNSRPQQP

8.86

-5.51

-3.01

LPTQPVRK

9.38

-8.43

-5.93

P53118

PHDLPSHL

9.09

-7.31

-4.81

VENPHDLP

9.95

-3.69

-1.19

ENPHDLPS

11.73

-0.79

1.71

P38216

RPSNPPPS

7.27

-7.63

-5.13

QYSRPSNP

11.21

-6.30

-3.80

PSNPPPSS

11.54

-2.71

-0.21

P53933

RPPPPPIP

6.38

-9.13

-6.64

RVAPPPLP

7.78

-8.68

-6.18

PPPLPNRQ

8.89

-8.84

-6.34

Q12446

LPPLPNQF

3.51

-9.26

-6.76

KHSLPPLP

5.83

-9.68

-7.18

APALPPAS

6.42

-7.50

-5.00

P38266

VPILPPRN

6.51

-8.24

-5.75

YPIEPSLD

6.86

-7.22

-4.72

MQPQPPQP

7.22

-6.51

-4.01

P40483

KPSVPPRN

8.70

-7.22

-4.72

PASKPSVP

10.72

-6.22

-3.72

PSVPPRNY

12.39

-3.83

-1.34

P07244

MPGMYPPG

8.35

-5.63

-3.13

P40563

RRAPPPVP

8.69

-7.36

-4.87

PPPVPKKP

10.34

-5.77

-3.27

NSEPPTPA

10.41

-2.23

0.27

Q07533

LPPLPDLD

3.52

-10.29

-7.79

LPPLPPLP

3.58

-10.99

-8.50

NNPLPPLP

5.07

-7.88

-5.38

P53901

QPPLPPIP

5.04

-8.67

-6.17

LPPLPTTS

5.42

-9.20

-6.70

SPKLPPLP

5.58

-9.32

-6.83

P37254

GPGNPNNG

9.98

-4.90

-2.41

Q12489

RPSAPPPG

8.00

-7.54

-5.04

SYSRPSAP

11.44

-5.03

-2.54

YSRPSAPP

12.67

-1.99

0.51

 


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