ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-11.PDB
Scoring matrix: PIN3_1CKB-11_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.91
Foldx random average score for Saccharomyces cerevisiae: 12.917

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 2622608
Proteins after disorder filtering: 5054
 Total fragments: 210807
Proteins after pattern filtering: 2363
 Total fragments: 20314
Proteins after MINT filtering: 25
 Total fragments: 536


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

12.91

-2.55

0.00

Best peptides

MRPIHPF

0.00

-3.93

-1.38

         
Interactors      
Q06604

GPRMPSR

5.94

-7.64

-5.09

LPTRPNK

6.65

-8.00

-5.45

NKPKPTP

6.65

-6.70

-4.15

P24583

LPPQPRK

5.94

-7.76

-5.21

APLPPQP

7.84

-6.98

-4.43

PPQPRKH

8.07

-6.80

-4.25

P38260

GPDDPTL

8.92

-3.95

-1.40

PDDPTLM

10.28

-2.76

-0.21

Q04322

PLDRPQL

6.28

-6.82

-4.27

PTLPPRR

7.13

-7.80

-5.25

SPPLPPR

7.28

-9.24

-6.69

Q12168

DPYFPQF

3.99

-4.97

-2.42

PPPVPNR

5.54

-8.77

-6.22

PVPKPNI

6.08

-7.01

-4.46

P15891

APPPPPR

5.80

-7.61

-5.06

PPPPPRR

5.91

-7.57

-5.02

TPEKKPK

7.07

-5.39

-2.84

Q12344

SPPLPPR

7.28

-9.24

-6.69

SPKLPPR

7.60

-9.02

-6.47

PPLPPRQ

7.82

-7.79

-5.24

P39521

TPHVPDR

6.40

-6.23

-3.68

PKPKPAQ

6.78

-6.38

-3.83

VPDRPPS

7.10

-6.08

-3.53

P40325

QPPRPPR

5.12

-7.79

-5.24

QPRPPPR

6.21

-7.76

-5.21

PRPPPRP

6.26

-7.61

-5.06

Q08601

RPVYPPP

6.35

-8.62

-6.07

PPGPPPM

6.52

-8.43

-5.88

RPMAPPP

7.38

-9.54

-6.99

P19812

PRRIPPT

5.58

-8.35

-5.80

PIFRPGN

7.10

-7.33

-4.78

PRPRRIP

7.39

-5.20

-2.65

Q12412

RPPQPPP

5.76

-8.36

-5.81

YDPNHRP

6.63

-3.61

-1.06

PPQPPPA

8.31

-7.86

-5.31

Q08412

LPTQPVR

6.48

-7.26

-4.71

PPQLPTR

8.16

-8.82

-6.27

SRPQQPE

8.59

-3.60

-1.05

P53118

PHDLPSH

7.85

-7.48

-4.93

ENPHDLP

11.72

-3.03

-0.48

NPHDLPS

11.99

-5.09

-2.54

P38216

RPSNPPP

6.86

-7.97

-5.42

SRPSNPP

8.14

-3.62

-1.07

PSNPPPS

9.05

-5.76

-3.21

P53933

RRPPPPP

5.48

-8.29

-5.74

RRRPPPP

5.70

-8.61

-6.06

RPPPPPI

5.80

-9.84

-7.29

Q12446

PPPPPAF

4.17

-7.79

-5.24

PPPPHRH

5.01

-7.38

-4.83

PPLPNQF

5.16

-5.97

-3.42

P38266

MPPPKPF

4.09

-5.26

-2.71

LPPPKPF

4.72

-7.35

-4.80

PPPKPFR

4.93

-8.70

-6.15

P40483

KPSVPPR

5.27

-7.99

-5.44

PASKPSV

7.84

-5.66

-3.11

PSVPPRN

9.09

-5.69

-3.14

P07244

PGMYPPG

9.26

-6.39

-3.84

EMPGMYP

10.39

-4.03

-1.48

P40563

PPPVPKK

5.74

-8.70

-6.15

PSERPKR

6.39

-6.46

-3.91

TPNVPTR

6.70

-6.80

-4.25

Q07533

IPPVPSR

4.72

-7.52

-4.97

PKAYPKL

5.89

-8.54

-5.99

LPPLPPL

6.69

-10.46

-7.91

P53901

MRPIPPL

2.72

-8.41

-5.86

LPPIPTR

4.98

-8.09

-5.54

SPNSHPH

6.79

-3.69

-1.14

P37254

GPGNPNN

9.63

-5.15

-2.60

PGNPNNG

11.26

-4.17

-1.62

PGPGNPN

11.31

-2.79

-0.24

Q12489

RPSAPPP

7.26

-7.85

-5.30

PSAPPPG

8.75

-6.05

-3.50

SRPSAPP

9.77

-3.94

-1.39

 


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