ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-8.PDB
Scoring matrix: PIN3_1CKA-8_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.78
Foldx random average score for Saccharomyces cerevisiae: 11.787

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1439367
Proteins after disorder filtering: 4728
 Total fragments: 127872
Proteins after pattern filtering: 2292
 Total fragments: 18905
Proteins after MINT filtering: 25
 Total fragments: 540


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

11.78

-1.88

0.00

Best peptides

FFPYLPPF

0.00

-1.65

0.23

         
Interactors      
Q06604

SPPPLPTR

4.87

-11.47

-9.59

EKPLLPTR

5.89

-10.22

-8.34

TPPSPPAK

6.30

-7.93

-6.05

P24583

ANAPLPPQ

5.25

-5.69

-3.81

NAPLPPQP

5.56

-5.82

-3.94

LPPQPRKH

7.54

-5.99

-4.11

P38260

GGPDDPTL

6.78

-5.51

-3.63

GGGPDDPT

11.50

-0.43

1.45

Q04322

TPPTLPPR

4.71

-11.53

-9.65

TSPPLPPR

4.72

-10.16

-8.28

QAPLDRPQ

5.37

-4.91

-3.03

Q12168

GPPPLPPR

4.16

-11.79

-9.91

DDPYFPQF

4.58

-6.82

-4.94

PPPLPPRA

6.38

-6.99

-5.11

P15891

AQPPLPSR

5.25

-10.42

-8.54

AAPPPPPR

6.33

-9.31

-7.43

PPPPPRRA

6.75

-6.80

-4.92

Q12344

SSPPLPPR

4.71

-9.88

-8.00

TSPKLPPR

5.11

-9.42

-7.54

SPPLPPRQ

5.76

-6.82

-4.94

P39521

DAQPKPKP

6.92

-5.76

-3.88

QPKPKPAQ

7.23

-6.05

-4.17

PHVPDRPP

7.84

-3.30

-1.42

P40325

QNPSLPWT

3.96

-7.14

-5.26

QPPRPPRP

5.60

-7.83

-5.95

PRPPPRPQ

6.51

-5.81

-3.93

Q08601

PPPGPPPM

5.48

-8.01

-6.13

APPPGPPP

5.76

-7.73

-5.85

NRPVYPPP

6.16

-5.87

-3.99

P19812

RPRRIPPT

4.84

-6.64

-4.76

DHSPIFRP

5.04

-4.77

-2.89

DAPQNPPP

5.30

-7.21

-5.33

Q12412

RPPQPPPA

6.46

-7.16

-5.28

YDPNHRPP

6.68

-4.79

-2.91

QPPPAYDP

7.73

-6.38

-4.50

Q08412

VPPQLPTR

5.73

-11.02

-9.14

KWQPLPPE

6.24

-5.43

-3.55

WQPLPPEP

6.79

-5.95

-4.07

P53118

NPHDLPSH

5.56

-6.97

-5.09

ENPHDLPS

7.33

-3.14

-1.26

PHDLPSHL

11.16

-0.88

1.00

P38216

SRPSNPPP

5.85

-6.21

-4.33

RPSNPPPS

8.07

-4.82

-2.94

PSNPPPSS

8.71

-3.64

-1.76

P53933

PPPPIPST

3.63

-8.15

-6.27

APPPLPNR

4.73

-11.57

-9.69

RPPPPPIP

5.61

-8.24

-6.36

Q12446

PAPALPPA

3.24

-7.77

-5.89

IPPTLPST

3.85

-8.98

-7.10

QFAPLPDP

4.53

-6.37

-4.49

P38266

SFPPPPLK

4.75

-7.22

-5.34

PPPLKPGQ

4.78

-7.87

-5.99

KPPVVPKK

5.47

-8.73

-6.85

P40483

SKPSVPPR

7.17

-10.07

-8.19

APASKPSV

7.80

-5.67

-3.79

KPSVPPRN

7.90

-4.96

-3.08

P07244

PGMYPPGH

8.84

-4.37

-2.49

MPGMYPPG

9.73

-4.45

-2.57

P40563

APPPVPKK

5.07

-8.89

-7.01

VNPGQLPP

6.92

-3.88

-2.00

NPGQLPPS

7.13

-6.40

-4.52

Q07533

SAPNLPLA

3.88

-7.60

-5.72

MNNPLPPL

5.03

-5.65

-3.77

LPPLPPLP

6.03

-7.55

-5.67

P53901

NSPKLPPL

4.12

-7.34

-5.46

NQPPLPPI

4.30

-8.42

-6.54

NDPIILPP

4.67

-5.02

-3.14

P37254

PGPGNPNN

7.09

-4.85

-2.97

VGPGPGNP

9.45

-3.32

-1.44

PGNPNNGA

10.70

-1.23

0.65

Q12489

SRPSAPPP

6.34

-6.26

-4.38

RPSAPPPG

8.04

-5.08

-3.20

PSAPPPGY

8.97

-4.36

-2.48

 


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