ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-7.PDB
Scoring matrix: PIN3_1CKA-7_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 9.27
Foldx random average score for Saccharomyces cerevisiae: 8.681

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7178
 Total fragments: 1439928
Proteins after disorder filtering: 4798
 Total fragments: 101862
Proteins after pattern filtering: 2303
 Total fragments: 18768
Proteins after MINT filtering: 26
 Total fragments: 484


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

9.27

-3.35

0.00

Best peptides

MRRWPPIW

0.00

-3.39

-0.04

         
Interactors      
Q06604

VKPAPPVS

3.15

-6.66

-3.31

PPSPPAKR

4.20

-7.66

-4.31

KPAPPVSR

4.36

-6.37

-3.02

P24583

APLPPQPR

5.14

-6.14

-2.79

PPQPRKHD

6.67

-5.82

-2.47

RANAPLPP

7.04

-4.35

-1.00

P38260

GPDDPTLM

7.77

-4.95

-1.60

Q04322

PPLPPRAD

5.29

-6.23

-2.88

PSKSPTSA

6.77

-3.92

-0.57

TSPPLPPR

6.93

-5.26

-1.91

Q12168

DDPYFPQF

4.46

-4.74

-1.39

IPPPVPNR

4.94

-5.45

-2.10

PPLPPRAN

5.10

-5.63

-2.28

P15891

AAPPPPPR

4.69

-6.38

-3.03

APPPPPRR

5.65

-10.35

-7.00

PSPAPAAK

5.78

-4.45

-1.10

Q12344

PPLPPRQN

4.42

-6.46

-3.11

PKLPPRGK

4.65

-6.07

-2.72

TSSPPLPP

5.83

-5.24

-1.89

P39521

PDRPPSQL

3.43

-5.68

-2.33

VQTPHVPD

4.66

-2.61

0.74

QPKPKPAQ

4.89

-5.06

-1.71

P40325

PRPPPRPQ

3.86

-6.06

-2.71

PPRPPRPA

4.29

-6.63

-3.28

RPPPRPQQ

4.52

-4.72

-1.37

Q08601

PMAPPPNQ

4.59

-5.68

-2.33

PPGPPPMA

4.79

-8.01

-4.66

RPMAPPPN

4.86

-5.19

-1.84

Q12532

PFKPYING

6.43

-3.44

-0.09

P19812

PQNPPPIL

4.03

-6.37

-3.02

PRRIPPTD

4.52

-7.02

-3.67

APQNPPPI

5.51

-5.56

-2.21

Q12412

PPQPPPAY

4.35

-6.58

-3.23

PQPPPAYD

4.47

-6.42

-3.07

YDPNHRPP

5.58

-3.22

0.13

Q08412

QPLPPEPL

3.90

-5.71

-2.36

LPPEPLDT

5.73

-4.44

-1.09

EDVPPQLP

6.15

-6.51

-3.16

P53118

VENPHDLP

5.66

-5.90

-2.55

ENPHDLPS

7.70

-1.09

2.26

P38216

RPSNPPPS

4.93

-6.03

-2.68

PSNPPPSS

5.56

-4.69

-1.34

YSRPSNPP

8.17

-3.47

-0.12

P53933

RRPPPPPI

3.04

-6.32

-2.97

RPPPPPIP

3.43

-6.77

-3.42

RRRPPPPP

3.79

-7.04

-3.69

Q12446

VPPPPPMR

2.49

-8.69

-5.34

VAPPPPPA

3.46

-6.76

-3.41

APPPPPQM

3.79

-6.26

-2.91

P38266

IMPPPKPF

3.00

-6.89

-3.54

VEPPPPPS

3.18

-4.35

-1.00

MPPPKPFR

3.29

-8.93

-5.58

P40483

PSVPPRNY

5.43

-5.56

-2.21

KPSVPPRN

6.31

-9.21

-5.86

KDAPASKP

6.72

-3.82

-0.47

P07244

PGMYPPGH

5.92

-5.42

-2.07

MPGMYPPG

7.58

-5.71

-2.36

EMPGMYPP

7.79

-3.53

-0.18

P40563

RRAPPPVP

4.13

-6.19

-2.84

RAPPPVPK

4.49

-4.77

-1.42

APPPVPKK

5.37

-4.13

-0.78

Q07533

KSDPHFPY

4.48

-4.19

-0.84

SDPHFPYG

4.50

-4.69

-1.34

VSSPKSPK

4.99

-4.05

-0.70

P53901

MRPIPPLP

3.94

-9.00

-5.65

RPIPPLPT

4.64

-5.23

-1.88

PKLPPLPT

4.65

-6.13

-2.78

P37254

VGPGPGNP

7.10

-4.36

-1.01

GPGNPNNG

7.86

-3.36

-0.01

Q12489

RPSAPPPG

4.89

-5.76

-2.41

PSAPPPGY

5.09

-5.68

-2.33

YSRPSAPP

7.99

-3.90

-0.55

 


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