ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-26.PDB
Scoring matrix: PIN3_1CKA-26_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 10.63
Foldx random average score for Saccharomyces cerevisiae: 9.931

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1566233
Proteins after disorder filtering: 4645
 Total fragments: 113136
Proteins after pattern filtering: 2306
 Total fragments: 21794
Proteins after MINT filtering: 26
 Total fragments: 611


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

10.63

-1.16

0.00

Best peptides

KDRPKILRK

0.00

-3.43

-2.27

         
Interactors      
Q06604

PRMPSRGRP

3.56

-5.77

-4.61

KPKPTPPSP

3.90

-6.97

-5.81

PTPPSPPAK

4.51

-7.97

-6.81

P24583

ERANAPLPP

5.32

-4.91

-3.75

ANAPLPPQP

6.29

-6.00

-4.84

NAPLPPQPR

6.33

-4.99

-3.83

P38260

GGPDDPTLM

9.21

-2.98

-1.82

Q04322

TSPPLPPRA

3.96

-7.44

-6.28

STPPTLPPR

5.43

-7.29

-6.13

TPPTLPPRR

6.56

-5.73

-4.57

Q12168

NRGPPPLPP

3.58

-5.54

-4.38

IPPPVPNRP

3.62

-5.88

-4.72

RGPPPLPPR

4.61

-7.55

-6.39

P15891

AAPPPPPRR

4.60

-8.21

-7.05

PPPPRRATP

5.16

-7.40

-6.24

APPPPPRRA

5.26

-7.51

-6.35

Q12344

TSPKLPPRG

5.33

-6.79

-5.63

SSPPLPPRQ

5.77

-7.51

-6.35

TTSSPPLPP

5.78

-4.19

-3.03

P39521

DAQPKPKPA

5.52

-4.90

-3.74

PHVPDRPPS

6.11

-6.78

-5.62

QPKPKPAQD

6.46

-4.53

-3.37

P40325

SQPPRPPRP

4.14

-7.78

-6.62

PPRPPRPAA

4.25

-8.22

-7.06

PRPPRPAAN

4.88

-6.24

-5.08

Q08601

YNRPVYPPP

4.71

-6.25

-5.09

QYAPPPGPP

4.98

-5.86

-4.70

YQRPMAPPP

5.06

-6.51

-5.35

Q12532

PFKPYINGG

4.59

-5.47

-4.31

P19812

EPRPRRIPP

4.07

-9.06

-7.90

RPRRIPPTD

5.08

-5.08

-3.92

SPIFRPGNI

5.51

-3.87

-2.71

Q12412

YDPNHRPPS

6.16

-7.44

-6.28

RPPQPPPAY

6.42

-6.58

-5.42

DPNHRPPSS

6.51

-5.11

-3.95

Q08412

KKKWQPLPP

3.79

-4.83

-3.67

PLPPEPLDT

5.26

-6.99

-5.83

KWQPLPPEP

5.26

-6.52

-5.36

P53118

VENPHDLPS

5.83

-4.32

-3.16

ENPHDLPSH

7.31

-5.09

-3.93

NPHDLPSHL

7.83

-2.74

-1.58

P38216

YSRPSNPPP

4.71

-5.96

-4.80

SRPSNPPPS

6.37

-4.87

-3.71

PSNPPPSSA

7.18

-3.56

-2.40

P53933

TRRRPPPPP

3.23

-6.22

-5.06

RTRRRPPPP

3.66

-5.90

-4.74

RVAPPPLPN

3.68

-6.37

-5.21

Q12446

NNRPVPPPP

3.06

-6.60

-5.44

PPPPRRGPA

3.63

-6.17

-5.01

PDPPQHNSP

4.34

-5.83

-4.67

P38266

SFPPPPLKP

2.84

-7.49

-6.33

KKPPVVPKK

3.56

-7.76

-6.60

KVPPVVPKK

3.75

-7.33

-6.17

P40483

ASKPSVPPR

4.90

-6.83

-5.67

SKPSVPPRN

6.43

-5.13

-3.97

KDAPASKPS

7.07

-4.83

-3.67

P07244

PGMYPPGHY

5.23

-5.45

-4.29

SEMPGMYPP

7.58

-6.18

-5.02

EMPGMYPPG

8.10

-4.86

-3.70

P40563

RAPPPVPKK

3.65

-7.88

-6.72

APPPVPKKP

4.93

-6.80

-5.64

RRAPPPVPK

5.12

-6.05

-4.89

Q07533

NNPLPPLPP

2.93

-6.45

-5.29

LPPLPPLPD

4.33

-6.54

-5.38

ESMNNPLPP

4.43

-5.29

-4.13

P53901

AMRPIPPLP

4.12

-6.26

-5.10

SNDPIILPP

4.26

-5.90

-4.74

NQPPLPPIP

4.56

-7.77

-6.61

P37254

VVGPGPGNP

7.04

-4.44

-3.28

PGNPNNGAQ

7.62

-4.14

-2.98

PGPGNPNNG

7.71

-3.99

-2.83

Q12489

YSRPSAPPP

4.82

-6.28

-5.12

SRPSAPPPG

6.42

-5.03

-3.87

PSAPPPGYE

7.13

-5.07

-3.91

 


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