ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-23.PDB
Scoring matrix: PIN3_1CKA-23_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 9.85
Foldx random average score for Saccharomyces cerevisiae: 12.766

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1656150
Proteins after disorder filtering: 4938
 Total fragments: 157305
Proteins after pattern filtering: 2322
 Total fragments: 15979
Proteins after MINT filtering: 25
 Total fragments: 460


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

9.85

-2.73

0.00

Best peptides

MESPPWF

0.00

-1.55

1.18

         
Interactors      
Q06604

PPSPPAK

4.51

-4.11

-1.39

KPKPTPP

4.55

-6.06

-3.33

SSPPPLP

4.85

-5.41

-2.69

P24583

APLPPQP

5.28

-5.08

-2.36

PLPPQPR

5.75

-5.57

-2.85

PPQPRKH

6.06

-4.03

-1.31

P38260

PDDPTLM

3.96

-4.64

-1.91

GGGPDDP

7.90

-3.44

-0.71

GPDDPTL

12.52

-1.86

0.86

Q04322

PTLPPRR

5.08

-6.65

-3.93

PPLPPRA

5.25

-4.76

-2.03

TSPPLPP

5.37

-4.66

-1.94

Q12168

RGPPPLP

4.18

-8.71

-5.99

PYFPQFR

4.75

-4.07

-1.35

PPVPNRP

4.82

-5.57

-2.85

P15891

PPPPPRR

4.53

-4.49

-1.77

APPPPPR

5.20

-4.66

-1.94

AAPPPPP

5.25

-4.83

-2.11

Q12344

TSSPPLP

4.05

-4.50

-1.77

PPLPPRQ

4.57

-4.19

-1.47

STSPKLP

4.97

-4.09

-1.36

P39521

PHVPDRP

5.16

-5.84

-3.11

PDRPPSQ

5.35

-5.19

-2.47

QPKPKPA

5.80

-4.88

-2.15

P40325

PPRPPRP

3.96

-7.64

-4.91

QQNPSLP

3.97

-5.23

-2.51

PRPPPRP

4.30

-6.27

-3.54

Q08601

PPGPPPM

4.81

-4.04

-1.31

YNRPVYP

4.87

-5.08

-2.36

PGPPPMA

5.12

-5.01

-2.28

Q12532

PFKPYIN

6.04

-5.40

-2.68

P19812

PQNPPPI

3.70

-5.22

-2.49

RPRRIPP

6.50

-8.45

-5.72

PRPRRIP

6.56

-5.91

-3.19

Q12412

PQPPPAY

5.23

-4.95

-2.23

PPQPPPA

6.14

-3.64

-0.92

PPPAYDP

7.72

-5.18

-2.45

Q08412

QPLPPEP

4.74

-5.80

-3.07

IELPTQP

4.83

-6.93

-4.21

PLPPEPL

5.09

-5.21

-2.48

P38216

PSNPPPS

5.53

-4.37

-1.65

YSRPSNP

6.11

-6.66

-3.94

SRPSNPP

8.49

-3.63

-0.90

P53933

RPPPPPI

3.77

-7.95

-5.22

RRRPPPP

3.93

-10.26

-7.54

PPPPPIP

4.13

-5.69

-2.97

Q12446

MSSPPPP

3.36

-5.52

-2.79

PPPPPAF

3.70

-4.62

-1.90

VPPPPPM

3.79

-5.38

-2.65

P38266

MPPPKPF

2.76

-5.71

-2.98

QPPPKPF

3.56

-4.82

-2.10

LPPPKPF

3.88

-5.40

-2.68

P40483

PSVPPRN

5.60

-4.70

-1.98

ASKPSVP

6.55

-4.62

-1.90

PASKPSV

7.04

-3.35

-0.63

P07244

MPGMYPP

6.50

-6.48

-3.76

EMPGMYP

9.38

-3.53

-0.80

P40563

PPVPKKP

4.80

-5.59

-2.86

PKVPERP

4.82

-5.56

-2.83

RAPPPVP

5.22

-8.14

-5.42

Q07533

PPLPPLP

3.96

-5.55

-2.82

MNNPLPP

4.05

-6.15

-3.43

KAYPKLP

4.55

-6.78

-4.05

P53901

RPIPPLP

3.31

-9.30

-6.58

PKLPPLP

4.05

-8.12

-5.39

PPLPPIP

4.08

-5.52

-2.79

P37254

PGNPNNG

6.99

-3.45

-0.73

GPGPGNP

7.34

-4.04

-1.31

PGPGNPN

9.90

-2.86

-0.13

Q12489

RPSAPPP

5.71

-7.13

-4.40

YSRPSAP

6.00

-3.89

-1.17

PSAPPPG

6.57

-4.11

-1.39

 


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