ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-17.PDB
Scoring matrix: PIN3_1CKA-17_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.89
Foldx random average score for Saccharomyces cerevisiae: 16.159

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1400545
Proteins after disorder filtering: 4632
 Total fragments: 86548
Proteins after pattern filtering: 2136
 Total fragments: 9285
Proteins after MINT filtering: 25
 Total fragments: 221


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.89

-2.16

0.00

Best peptides

FRWIMGRSL

0.00

1.27

3.43

         
Interactors      
Q06604

EKGPRMPSR

12.05

-4.49

-2.33

PAPPVSRST

12.31

-4.64

-2.48

LPTRPNKAE

12.35

-6.55

-4.39

P24583

LPPQPRKHD

9.46

-9.23

-7.07

APLPPQPRK

14.07

-7.66

-5.50

P38260

GGGPDDPTL

13.98

-4.72

-2.56

Q04322

GNATPSKSP

13.71

-4.79

-2.63

DQAPLDRPQ

15.72

-3.87

-1.71

QAPLDRPQL

15.82

-4.11

-1.95

Q12168

QHPVPKPNI

11.03

-7.25

-5.09

VPNRPGGTT

11.35

-6.57

-4.41

NDDPYFPQF

12.28

-5.07

-2.91

P15891

KEPVKTPSP

9.81

-5.44

-3.28

KSFTPSKSP

10.93

-4.86

-2.70

AAQPPLPSR

11.60

-5.64

-3.48

Q12344

PPLPPRQNV

14.02

-7.54

-5.38

PKLPPRGKQ

14.18

-5.35

-3.19

TSSPPLPPR

15.72

-6.52

-4.36

P39521

TPHVPDRPP

13.02

-8.46

-6.30

VDAQPKPKP

15.75

-6.77

-4.61

PHVPDRPPS

15.78

-4.20

-2.04

P40325

PRPQQNPSL

9.84

-5.67

-3.51

SRPHQRPST

10.70

-3.63

-1.47

YVQPGDPRL

11.06

-5.85

-3.69

Q08601

YAPPPGPPP

13.89

-8.15

-5.99

YQRPMAPPP

15.34

-9.31

-7.15

PGPPPMAYN

15.99

-5.45

-3.29

P19812

NSPEASPSL

8.79

-3.43

-1.27

HSPIFRPGN

13.11

-2.74

-0.58

AKTSPSNSP

14.61

-5.04

-2.88

Q12412

PPPAYDPNH

14.66

-5.65

-3.49

AYDPNHRPP

15.92

-5.09

-2.93

QPPPAYDPN

16.01

-5.78

-3.62

Q08412

LPPEPLDTT

12.97

-6.27

-4.11

LPTQPVRKN

13.29

-9.53

-7.37

DVPPQLPTR

14.20

-5.11

-2.95

P53118

ENPHDLPSH

10.34

-2.82

-0.66

NPHDLPSHL

15.62

-7.18

-5.02

P38216

QYSRPSNPP

16.07

-5.82

-3.66

P53933

PPPPPIPST

10.99

-8.05

-5.89

NDLPMELPH

12.65

-4.63

-2.47

PPPIPSTQK

13.10

-7.14

-4.98

Q12446

PPPPPHRHV

8.63

-10.88

-8.72

FPIPEIPST

9.48

-6.42

-4.26

PPPPPRASR

9.48

-8.57

-6.41

P38266

NIYPIEPSL

6.69

-6.37

-4.21

PPKPFRRSQ

8.24

-7.39

-5.23

PRPPPSRSS

9.71

-7.64

-5.48

P40483

PSVPPRNYF

13.13

-7.22

-5.06

DAPASKPSV

13.58

-3.23

-1.07

KDAPASKPS

16.09

-2.82

-0.66

P07244

TSEMPGMYP

14.39

-6.69

-4.53

P40563

NSQPQGPSD

9.73

-3.76

-1.60

PSERPKRRA

13.95

-7.21

-5.05

PPTPAGTPN

14.40

-4.52

-2.36

Q07533

PHFPYGTWK

11.27

-4.86

-2.70

PPVPSRYSD

11.41

-6.24

-4.08

NPLPPLPPL

11.60

-8.34

-6.18

P53901

PNSHPHPSG

11.99

-4.18

-2.02

LPPIPTRDD

12.27

-7.83

-5.67

LPPLPTTSN

12.29

-7.36

-5.20

P37254

GPGPGNPNN

15.96

-6.18

-4.02

Q12489

YSRPSAPPP

16.15

-5.99

-3.83

 


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