ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-15.PDB
Scoring matrix: PIN3_1CKA-15_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 10.62
Foldx random average score for Saccharomyces cerevisiae: 9.858

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1329653
Proteins after disorder filtering: 4455
 Total fragments: 64239
Proteins after pattern filtering: 2147
 Total fragments: 10776
Proteins after MINT filtering: 24
 Total fragments: 281


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

10.62

-0.49

0.00

Best peptides

FFRHIPKKM

0.00

1.56

2.05

         
Interactors      
Q06604

LLPTRPNKA

5.50

-2.94

-2.45

TPPSPPAKR

6.36

-4.91

-4.42

SPPPLPTRR

7.30

-3.56

-3.07

P24583

PLPPQPRKH

7.14

-3.03

-2.54

LPPQPRKHD

8.15

-5.69

-5.20

Q04322

TPPTLPPRR

6.70

-4.60

-4.11

TPSKSPTSA

7.29

-2.90

-2.41

TSPPLPPRA

8.37

-0.89

-0.40

Q12168

HPVPKPNID

6.10

-2.02

-1.53

PLPPRANVQ

6.98

-2.51

-2.02

DDPYFPQFR

7.81

-2.38

-1.89

P15891

APPPPPRRA

7.38

-4.88

-4.39

TPEKKPKEN

7.57

-3.26

-2.77

RRATPEKKP

8.14

-2.92

-2.43

Q12344

TSPKLPPRG

7.73

-2.04

-1.55

SSPPLPPRQ

8.17

-1.34

-0.85

PKLPPRGKQ

9.62

-6.07

-5.58

P39521

HVPDRPPSQ

6.37

-1.34

-0.85

QTPHVPDRP

6.43

-2.63

-2.14

QPKPKPAQD

7.45

-3.22

-2.73

P40325

RPHQRPSTM

4.17

-5.55

-5.06

LPWTYPPRF

5.85

-5.91

-5.42

RPSTMPATS

6.72

-3.63

-3.14

Q08601

RPMAPPPNQ

5.51

-4.54

-4.05

PMAPPPNQQ

8.13

-3.07

-2.58

MAYNRPVYP

8.42

-2.68

-2.19

P19812

RPRRIPPTD

6.90

-3.84

-3.35

SPIFRPGNI

7.19

-4.02

-3.53

APQNPPPIL

7.68

-4.92

-4.43

Q12412

RPPQPPPAY

6.38

-4.37

-3.88

PPAYDPNHR

7.00

-4.92

-4.43

DPNHRPPSS

7.14

-2.66

-2.17

Q08412

LPTQPVRKN

7.51

-4.50

-4.01

VPPQLPTRT

7.90

-3.53

-3.04

ELPTQPVRK

8.00

-4.01

-3.52

P53118

NPHDLPSHL

6.80

-4.15

-3.66

P38216

RPSNPPPSS

7.47

-5.05

-4.56

PSNPPPSSA

9.41

-1.49

-1.00

P53933

PPPPIPSTQ

6.32

-4.13

-3.64

APPPLPNRQ

6.65

-4.63

-4.14

RRPPPPPIP

7.84

-2.33

-1.84

Q12446

FPFPVPQQQ

4.41

-4.63

-4.14

LPPASPEVR

5.62

-6.24

-5.75

FPFPIPEIP

5.72

-3.91

-3.42

P38266

KPPVVPKKK

4.58

-5.51

-5.02

QPPVPVRMQ

5.12

-6.16

-5.67

VPPVVPKKN

5.15

-4.86

-4.37

P40483

KPSVPPRNY

5.35

-5.87

-5.38

APASKPSVP

8.54

-2.71

-2.22

SKPSVPPRN

9.04

-1.40

-0.91

P07244

MPGMYPPGH

8.22

-5.20

-4.71

PGMYPPGHY

9.67

-2.01

-1.52

P40563

NPGQLPPSL

6.13

-3.18

-2.69

APPPVPKKP

7.86

-4.95

-4.46

KRRAPPPVP

8.01

-3.45

-2.96

Q07533

KSPKAYPKL

7.76

-2.52

-2.03

IPPVPSRYS

8.55

-4.51

-4.02

PLPPLPDLD

8.66

-1.77

-1.28

P53901

KLPPLPTTS

7.34

-2.35

-1.86

PLPPIPTRD

7.78

-1.35

-0.86

NSPKLPPLP

8.25

-0.34

0.15

P37254

GPGNPNNGA

9.45

-2.79

-2.30

Q12489

RPSAPPPGY

6.91

-3.84

-3.35

QSYSRPSAP

8.92

-1.85

-1.36

 


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