ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-11.PDB
Scoring matrix: PIN3_1CKA-11_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 10.54
Foldx random average score for Saccharomyces cerevisiae: 9.984

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1552598
Proteins after disorder filtering: 4919
 Total fragments: 130004
Proteins after pattern filtering: 2344
 Total fragments: 18237
Proteins after MINT filtering: 25
 Total fragments: 500


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

10.54

-1.96

0.00

Best peptides

MRPIHPP

0.00

-3.10

-1.14

         
Interactors      
Q06604

KPTPPSP

3.87

-7.00

-5.04

KPAPPVS

4.85

-6.29

-4.33

TPPSPPA

5.75

-5.37

-3.41

P24583

LPPQPRK

4.90

-7.48

-5.52

APLPPQP

4.94

-6.93

-4.97

PPQPRKH

6.27

-7.52

-5.56

P38260

GPDDPTL

8.10

-6.39

-4.43

PDDPTLM

8.89

-3.88

-1.92

Q04322

TPPTLPP

4.94

-5.71

-3.75

PPLPPRA

5.14

-7.77

-5.81

PPTLPPR

6.20

-7.67

-5.71

Q12168

GPPPLPP

5.13

-7.06

-5.10

PPLPPRA

5.14

-7.77

-5.81

PPPVPNR

5.18

-7.71

-5.75

P15891

PPPPPRR

5.25

-9.08

-7.12

APPPPPR

5.30

-8.15

-6.19

PPPPRRA

5.38

-6.50

-4.54

Q12344

PPLPPRQ

4.89

-7.93

-5.97

SPPLPPR

6.42

-7.45

-5.49

PKLPPRG

6.42

-7.29

-5.33

P39521

PDRPPSQ

5.04

-6.94

-4.98

VQTPHVP

5.58

-3.24

-1.28

QPKPKPA

6.00

-5.60

-3.64

P40325

PRPPPRP

3.56

-7.23

-5.27

RPPPRPQ

4.40

-5.90

-3.94

PPRPPRP

4.46

-7.78

-5.82

Q08601

RPVYPPP

3.90

-6.45

-4.49

RPMAPPP

4.46

-7.52

-5.56

PPPGPPP

5.01

-7.71

-5.75

P19812

PRRIPPT

5.18

-6.45

-4.49

APQNPPP

5.37

-6.52

-4.56

SPIFRPG

6.02

-4.56

-2.60

Q12412

RPPQPPP

2.93

-7.46

-5.50

YDPNHRP

4.59

-5.73

-3.77

PPQPPPA

5.13

-7.75

-5.79

Q08412

SRPQQPE

5.64

-3.03

-1.07

KWQPLPP

5.80

-6.00

-4.04

LPTQPVR

5.98

-6.59

-4.63

P53118

PHDLPSH

6.82

-5.05

-3.09

NPHDLPS

7.55

-5.63

-3.67

ENPHDLP

8.63

-1.57

0.39

P38216

RPSNPPP

4.26

-7.08

-5.12

SRPSNPP

5.64

-3.08

-1.12

PSNPPPS

7.09

-6.48

-4.52

P53933

RRPPPPP

2.84

-6.99

-5.03

RRRPPPP

3.25

-6.92

-4.96

PPPPPIP

4.47

-8.03

-6.07

Q12446

NRPVPPP

3.10

-5.90

-3.94

RPVPPPP

3.85

-8.38

-6.42

PPPPHRH

3.89

-6.38

-4.42

P38266

MQPQPPQ

3.40

-6.15

-4.19

EPPPPPS

4.45

-7.70

-5.74

PPPPLKP

4.48

-8.16

-6.20

P40483

KPSVPPR

4.36

-6.94

-4.98

APASKPS

6.93

-4.78

-2.82

ASKPSVP

8.69

-3.25

-1.29

P07244

EMPGMYP

7.31

-4.06

-2.10

PGMYPPG

8.02

-4.85

-2.89

MPGMYPP

8.27

-6.14

-4.18

P40563

NPGQLPP

4.50

-6.23

-4.27

PPPVPKK

4.93

-8.56

-6.60

EPPTPAG

5.31

-6.06

-4.10

Q07533

IPPVPSR

4.35

-6.11

-4.15

PPLPPLP

4.75

-7.76

-5.80

NPLPPLP

4.92

-6.86

-4.90

P53901

MRPIPPL

1.82

-7.76

-5.80

RPIPPLP

4.24

-7.08

-5.12

DPIILPP

4.42

-6.23

-4.27

P37254

GPGNPNN

8.51

-5.45

-3.49

GPGPGNP

9.07

-3.56

-1.60

PGNPNNG

9.31

-2.25

-0.29

Q12489

RPSAPPP

4.38

-6.89

-4.93

SRPSAPP

6.45

-3.29

-1.33

PSAPPPG

6.84

-6.22

-4.26

 


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