ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-9.PDB
Scoring matrix: PEX13_1N5Z-9_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.63
Foldx random average score for Saccharomyces cerevisiae: 12.747

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1354357
Proteins after disorder filtering: 4322
 Total fragments: 52022
Proteins after pattern filtering: 2153
 Total fragments: 11835
Proteins after MINT filtering: 6
 Total fragments: 60


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.63

-2.15

0.00

Best peptides

REWRPPRY

0.00

-12.03

-9.88

         
Interactors      
Q04370

DIPRPPFS

8.34

-10.11

-7.96

DEDIPRPP

9.26

-7.62

-5.47

IPRPPFSS

11.17

-6.89

-4.74

P40450

SPKLFPRL

5.99

-10.48

-8.33

LPQLPPPP

8.34

-9.40

-7.25

PPPLPDLF

8.35

-10.36

-8.21

P47135

PRASPSRS

8.36

-9.21

-7.06

FPLPPPNV

9.59

-8.16

-6.01

YPGVFPVS

9.78

-7.50

-5.35

P15274

PKNKPGWV

8.64

-6.85

-4.70

VYPPPPKP

8.95

-8.90

-6.75

PPPKPSYN

9.02

-11.21

-9.06

P53112

PNGIPGID

10.67

-6.49

-4.34

Q08446

HSPISPLK

10.78

-6.26

-4.11

 


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