ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-7.PDB
Scoring matrix: PEX13_1N5Z-7_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 21.18
Foldx random average score for Saccharomyces cerevisiae: 16.614

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1305522
Proteins after disorder filtering: 4483
 Total fragments: 65261
Proteins after pattern filtering: 2061
 Total fragments: 10410
Proteins after MINT filtering: 7
 Total fragments: 51


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

21.18

-3.62

0.00

Best peptides

FFRRFPRS

0.00

-9.54

-5.92

         
Interactors      
Q04370

DIPRPPFS

6.92

-11.07

-7.45

IPRPPFSS

12.22

-5.38

-1.76

PRPPFSSH

14.34

-5.66

-2.04

P40450

PKLFPRLS

9.73

-9.03

-5.41

SPKLFPRL

10.44

-9.61

-5.99

PPPPLPQS

12.39

-7.87

-4.25

P47135

PRASPSRS

10.17

-8.57

-4.95

KTPRASPS

11.11

-7.79

-4.17

YPGVFPVS

11.33

-6.80

-3.18

P15274

YPPPPKPS

11.85

-7.50

-3.88

PPPKPSYN

12.37

-9.16

-5.54

PKNKPGWV

13.52

-9.67

-6.05

P53112

PNGIPGID

14.62

-6.93

-3.31

Q08446

HSPISPLK

14.15

-6.90

-3.28

Q12110

PVAPSPNH

16.20

-4.43

-0.81

 


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