ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-29.PDB
Scoring matrix: PEX13_1N5Z-29_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.86
Foldx random average score for Saccharomyces cerevisiae: 15.735

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1482806
Proteins after disorder filtering: 4072
 Total fragments: 54716
Proteins after pattern filtering: 2002
 Total fragments: 11082
Proteins after MINT filtering: 5
 Total fragments: 50


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.86

1.20

0.00

Best peptides

RRWWRRRRRK

0.00

-8.46

-9.66

         
Interactors      
P40450

SSPKLFPRLS

8.73

-11.70

-12.90

APPPLPDLFK

11.60

-10.76

-11.96

PPPPLPESLS

12.20

-9.55

-10.75

P47135

SYPGVFPVSG

12.75

-6.53

-7.73

KTPRASPSRS

12.92

-8.16

-9.36

GYFSYPGVFP

13.15

-7.60

-8.80

Q04370

PRPPFSSHSD

12.19

-7.56

-8.76

EDIPRPPFSS

12.45

-6.40

-7.60

DEDIPRPPFS

13.18

-4.75

-5.95

Q12110

PVAPSPNHRS

13.01

-9.73

-10.93

P15274

PPPPKPSYNS

13.43

-7.65

-8.85

VVYPPPPKPS

14.23

-7.93

-9.13

PGWVVYPPPP

14.50

-5.31

-6.51

 


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