ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-26.PDB
Scoring matrix: PEX13_1N5Z-26_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.3
Foldx random average score for Saccharomyces cerevisiae: 13.862

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7178
 Total fragments: 1337095
Proteins after disorder filtering: 4293
 Total fragments: 67236
Proteins after pattern filtering: 2207
 Total fragments: 16114
Proteins after MINT filtering: 7
 Total fragments: 80


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

18.30

-1.98

0.00

Best peptides

DDPPRRRPH

0.00

-9.63

-7.65

         
Interactors      
Q04370

DEDIPRPPF

6.93

-8.18

-6.20

IPRPPFSSH

9.63

-6.42

-4.44

EDIPRPPFS

10.22

-5.91

-3.93

P40450

SSPKLFPRL

8.82

-7.06

-5.08

PPPPPPPPL

8.86

-8.69

-6.71

PPPPPPLPQ

9.04

-8.25

-6.27

P47135

KTPRASPSR

10.33

-7.45

-5.47

QCPFPLPPP

10.71

-8.74

-6.76

CPFPLPPPN

10.90

-6.88

-4.90

P15274

YPPPPKPSY

6.90

-8.91

-6.93

QNPKNKPGW

8.95

-8.45

-6.47

VYPPPPKPS

10.17

-7.39

-5.41

P53112

ISPNGIPGI

11.10

-7.11

-5.13

SISPNGIPG

13.40

-5.00

-3.02

Q08446

SHSPISPLK

10.34

-6.78

-4.80

SSHSPISPL

12.48

-3.68

-1.70

Q12110

SPVAPSPNH

11.37

-6.30

-4.32

PVAPSPNHR

11.79

-7.66

-5.68

GSPVAPSPN

13.32

-5.31

-3.33

 


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