ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-18.PDB
Scoring matrix: PEX13_1N5Z-18_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 18.89
Foldx random average score for Saccharomyces cerevisiae: 17.471

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1832194
Proteins after disorder filtering: 4609
 Total fragments: 116601
Proteins after pattern filtering: 2280
 Total fragments: 18267
Proteins after MINT filtering: 7
 Total fragments: 69


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

18.89

2.75

0.00

Best peptides

FPPIRPIRCL

0.00

0.35

-2.40

         
Interactors      
Q04370

DIPRPPFSSH

12.21

-1.50

-4.25

EDIPRPPFSS

13.55

-1.93

-4.68

IPRPPFSSHS

16.70

-3.25

-6.00

P40450

SPKLFPRLSS

9.57

-5.17

-7.92

PPPLPESLSM

10.10

-6.39

-9.14

PPPPPPPLPQ

10.88

-6.63

-9.38

P47135

TPRASPSRSK

10.34

-3.04

-5.79

ASTLSPGQPL

10.38

-6.57

-9.32

YPGVFPVSGF

11.55

-5.67

-8.43

P15274

PPPKPSYNSD

12.32

-3.38

-6.13

PPPPKPSYNS

12.66

-5.52

-8.27

VVYPPPPKPS

12.79

-4.87

-7.63

P53112

FSISPNGIPG

14.39

-4.95

-7.71

SISPNGIPGI

15.62

-2.67

-5.42

SPNGIPGIDT

17.35

-1.76

-4.51

Q08446

NSSHSPISPL

10.81

-4.57

-7.33

Q12110

SPVAPSPNHR

13.77

-2.73

-5.48

GSPVAPSPNH

15.26

-1.41

-4.17

NSQGSPVAPS

16.61

-2.03

-4.79

 


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