ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-16.PDB
Scoring matrix: PEX13_1N5Z-16_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.91
Foldx random average score for Saccharomyces cerevisiae: 17.169

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1917655
Proteins after disorder filtering: 4759
 Total fragments: 154738
Proteins after pattern filtering: 2323
 Total fragments: 19376
Proteins after MINT filtering: 7
 Total fragments: 71


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.91

3.25

0.00

Best peptides

FMPLRSIRP

0.00

-3.43

-6.68

         
Interactors      
Q04370

DIPRPPFSS

11.89

-3.17

-6.42

EDIPRPPFS

13.92

0.93

-2.32

PRPPFSSHS

15.26

-0.74

-3.99

P40450

LPQLPPPPP

8.45

-8.25

-11.50

HDLVTPPAP

9.61

-4.35

-7.60

SPKLFPRLS

10.20

-4.80

-8.05

P47135

KEQCPFPLP

9.53

-5.44

-8.69

YFSYPGVFP

9.68

-2.35

-5.60

ASTLSPGQP

10.73

-3.96

-7.21

P15274

DDQNPKNKP

8.72

-4.10

-7.35

PPPKPSYNS

10.44

-3.45

-6.70

VVYPPPPKP

12.29

-4.74

-7.99

P53112

FSISPNGIP

10.20

-3.27

-6.52

PNGIPGIDT

15.54

0.87

-2.38

SISPNGIPG

15.99

-0.53

-3.78

Q08446

NSSHSPISP

8.95

-3.17

-6.42

Q12110

NSQGSPVAP

13.20

-1.44

-4.69

SPVAPSPNH

14.51

-0.57

-3.82

QGSPVAPSP

15.33

-1.62

-4.87

 


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