ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-15.PDB
Scoring matrix: PEX13_1N5Z-15_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 20.31
Foldx random average score for Saccharomyces cerevisiae: 14.825

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1370472
Proteins after disorder filtering: 4137
 Total fragments: 41976
Proteins after pattern filtering: 1767
 Total fragments: 5747
Proteins after MINT filtering: 5
 Total fragments: 20


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

20.31

0.89

0.00

Best peptides

RWWIYHRIK

0.00

-6.70

-7.59

         
Interactors      
P40450

SSPKLFPRL

9.82

-5.35

-6.24

PPPLPQSLL

10.78

-7.11

-8.00

APPLPNGLL

11.41

-4.85

-5.74

P47135

PFPLPPPNV

12.73

-4.85

-5.74

KTPRASPSR

13.08

-4.03

-4.92

NFGPLPEPL

14.12

-2.68

-3.57

Q08446

SHSPISPLK

12.69

-1.07

-1.96

Q04370

DEDIPRPPF

12.90

-4.43

-5.32

P15274

WVVYPPPPK

13.82

-3.64

-4.53

PPPKPSYNS

13.82

-4.03

-4.92

YPPPPKPSY

13.87

-5.45

-6.34

 


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