ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-11.PDB
Scoring matrix: PEX13_1N5Z-11_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.09
Foldx random average score for Saccharomyces cerevisiae: 11.825

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 2084527
Proteins after disorder filtering: 4951
 Total fragments: 149549
Proteins after pattern filtering: 2338
 Total fragments: 17281
Proteins after MINT filtering: 7
 Total fragments: 76


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.09

-1.58

0.00

Best peptides

FRPRLPR

0.00

-7.10

-5.52

         
Interactors      
Q04370

DIPRPPF

5.35

-8.11

-6.53

EDIPRPP

7.92

-2.79

-1.21

IPRPPFS

8.24

-4.97

-3.39

P40450

PPPPLPQ

6.53

-7.06

-5.48

SSPKLFP

6.71

-4.98

-3.40

PPPPPPL

6.77

-7.05

-5.47

P47135

PRASPSR

5.73

-6.17

-4.59

FPLPPPN

5.89

-6.92

-5.34

CPFPLPP

7.78

-5.42

-3.84

P15274

PPPKPSY

5.32

-7.25

-5.67

PKNKPGW

6.09

-6.42

-4.84

VYPPPPK

6.87

-5.02

-3.44

P53112

PNGIPGI

7.55

-4.77

-3.19

ISPNGIP

11.51

-0.77

0.81

Q08446

HSPISPL

7.51

-2.64

-1.06

SPISPLK

8.24

-4.86

-3.28

SHSPISP

11.30

-2.74

-1.16

Q12110

SPVAPSP

9.28

-4.82

-3.24

PVAPSPN

10.07

-3.41

-1.83

GSPVAPS

11.36

-2.53

-0.95

 


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