ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-28.PDB
Scoring matrix: PEX13_1JQQ-28_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.73
Foldx random average score for Saccharomyces cerevisiae: 15.999

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1514405
Proteins after disorder filtering: 4289
 Total fragments: 62534
Proteins after pattern filtering: 2081
 Total fragments: 11677
Proteins after MINT filtering: 6
 Total fragments: 51


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.73

9.24

0.00

Best peptides

RDPWRPRKKK

0.00

-5.51

-14.75

         
Interactors      
Q04370

EDIPRPPFSS

12.85

1.42

-7.82

DIPRPPFSSH

13.97

-4.30

-13.54

IPRPPFSSHS

14.05

-0.19

-9.43

P40450

APPPLPDLFK

11.42

-3.03

-12.27

PPPLPESLSM

12.05

-3.92

-13.16

PPLPDLFKTK

12.42

-1.65

-10.89

P47135

SKTPRASPSR

10.23

-2.93

-12.17

TPRASPSRSK

11.15

0.30

-8.94

YFSYPGVFPV

11.92

-4.30

-13.54

P15274

YPPPPKPSYN

10.67

-4.88

-14.12

GWVVYPPPPK

11.32

0.71

-8.53

QNPKNKPGWV

13.34

-3.78

-13.02

Q08446

SSHSPISPLK

12.25

-0.16

-9.40

Q12110

SPVAPSPNHR

13.02

-1.69

-10.93

PVAPSPNHRS

15.18

-2.68

-11.92

 


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