ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-27.PDB
Scoring matrix: PEX13_1JQQ-27_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 13.85
Foldx random average score for Saccharomyces cerevisiae: 17.731

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1713449
Proteins after disorder filtering: 4701
 Total fragments: 155007
Proteins after pattern filtering: 2323
 Total fragments: 21424
Proteins after MINT filtering: 7
 Total fragments: 86


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

13.85

-0.97

0.00

Best peptides

FHRPRWPRK

0.00

-6.42

-5.45

         
Interactors      
Q04370

PRPPFSSHS

8.92

-6.81

-5.84

IPRPPFSSH

9.79

-6.62

-5.65

EDIPRPPFS

10.08

-5.18

-4.21

P40450

LPPPPPPPP

8.14

-9.53

-8.56

VPPPPPPPP

8.38

-8.39

-7.42

AVPPPPPPP

9.10

-8.33

-7.36

P47135

SKTPRASPS

7.34

-5.09

-4.12

FPLPPPNVN

8.42

-7.39

-6.42

TPRASPSRS

9.01

-6.60

-5.63

P15274

VYPPPPKPS

9.13

-7.95

-6.98

YPPPPKPSY

9.22

-9.12

-8.15

VVYPPPPKP

9.33

-8.26

-7.29

P53112

FSISPNGIP

11.61

-5.69

-4.72

SPNGIPGID

13.06

-2.74

-1.77

ISPNGIPGI

15.88

-3.53

-2.56

Q08446

SHSPISPLK

7.26

-6.95

-5.98

SSHSPISPL

11.04

-3.85

-2.88

Q12110

SPVAPSPNH

10.73

-4.49

-3.52

SQGSPVAPS

11.21

-3.37

-2.40

PVAPSPNHR

12.32

-4.65

-3.68

 


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