ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-23.PDB
Scoring matrix: PEX13_1JQQ-23_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 16.13
Foldx random average score for Saccharomyces cerevisiae: 14.138

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1779686
Proteins after disorder filtering: 4865
 Total fragments: 98032
Proteins after pattern filtering: 2075
 Total fragments: 7986
Proteins after MINT filtering: 7
 Total fragments: 28


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

16.13

0.35

0.00

Best peptides

RYLRRYY

0.00

-5.65

-6.00

         
Interactors      
Q04370

DIPRPPF

10.68

-3.21

-3.56

P40450

PKLFPRL

7.04

-3.36

-3.71

LPQLPPP

9.47

-4.34

-4.69

SPKLFPR

10.84

-4.08

-4.43

P47135

SYPGVFP

9.96

-2.37

-2.72

KTPRASP

10.08

-5.68

-6.03

LSPGQPL

10.35

-3.79

-4.14

P15274

PPPKPSY

9.93

-4.02

-4.37

PKNKPGW

11.69

-3.05

-3.40

QNPKNKP

11.79

-4.53

-4.88

P53112

ISPNGIP

13.48

-3.19

-3.54

SPNGIPG

13.78

-2.08

-2.43

Q08446

SPISPLK

13.94

-2.94

-3.29

Q12110

SPVAPSP

13.78

-2.39

-2.74

 


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