ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-19.PDB
Scoring matrix: PEX13_1JQQ-19_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.72
Foldx random average score for Saccharomyces cerevisiae: 16.935

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1542241
Proteins after disorder filtering: 4544
 Total fragments: 73292
Proteins after pattern filtering: 2104
 Total fragments: 8616
Proteins after MINT filtering: 7
 Total fragments: 36


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

17.72

-1.04

0.00

Best peptides

RDFKRGRRL

0.00

-5.91

-4.87

         
Interactors      
Q04370

IPRPPFSSH

12.13

-6.46

-5.42

PRPPFSSHS

14.54

-6.66

-5.62

P40450

SSPKLFPRL

10.92

-5.95

-4.91

PPLPNGLLS

12.56

-5.62

-4.58

LVTPPAPPL

13.41

-6.86

-5.82

P47135

PRASPSRSK

11.77

-8.52

-7.48

KTPRASPSR

13.32

-5.48

-4.44

STLSPGQPL

13.98

-6.72

-5.68

P15274

PKNKPGWVV

10.62

-7.09

-6.05

QNPKNKPGW

13.88

-3.93

-2.89

DDQNPKNKP

14.16

-8.93

-7.89

P53112

SISPNGIPG

14.91

-4.99

-3.95

PNGIPGIDT

16.23

-2.67

-1.63

Q08446

SHSPISPLK

16.21

-3.48

-2.44

Q12110

SPVAPSPNH

14.62

-3.97

-2.93

QGSPVAPSP

15.14

-7.63

-6.59

 


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