ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-18.PDB
Scoring matrix: PEX13_1JQQ-18_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 21.13
Foldx random average score for Saccharomyces cerevisiae: 25.464

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1963469
Proteins after disorder filtering: 4641
 Total fragments: 152361
Proteins after pattern filtering: 2284
 Total fragments: 18552
Proteins after MINT filtering: 7
 Total fragments: 63


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

21.13

4.11

0.00

Best peptides

RIPIRRRRCF

0.00

-3.90

-8.01

         
Interactors      
Q04370

DIPRPPFSSH

15.76

-5.33

-9.44

EDIPRPPFSS

19.58

-0.11

-4.22

IPRPPFSSHS

19.76

3.43

-0.68

P40450

SPKLFPRLSS

11.73

-6.67

-10.78

PPPLPESLSM

14.21

-3.67

-7.78

PPPPPLPQSL

15.27

-3.28

-7.38

P47135

YPGVFPVSGF

13.62

-6.83

-10.94

ASTLSPGQPL

14.04

-4.31

-8.41

TPRASPSRSK

14.73

-1.54

-5.65

P15274

DDQNPKNKPG

13.90

-1.67

-5.78

PKNKPGWVVY

13.96

-3.64

-7.75

NPKNKPGWVV

15.82

-2.67

-6.78

P53112

SISPNGIPGI

15.95

-0.30

-4.41

FSISPNGIPG

17.88

-1.18

-5.29

SPNGIPGIDT

24.17

-3.20

-7.31

Q08446

NSSHSPISPL

14.43

-3.26

-7.37

Q12110

SPVAPSPNHR

16.33

1.88

-2.23

NSQGSPVAPS

20.63

-0.64

-4.75

QGSPVAPSPN

21.62

1.67

-2.44

 


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