ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-17.PDB
Scoring matrix: PEX13_1JQQ-17_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.38
Foldx random average score for Saccharomyces cerevisiae: 16.336

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1410254
Proteins after disorder filtering: 4592
 Total fragments: 94946
Proteins after pattern filtering: 2139
 Total fragments: 10175
Proteins after MINT filtering: 6
 Total fragments: 31


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.38

-2.01

0.00

Best peptides

YRKRPGRSV

0.00

-7.25

-5.24

         
Interactors      
Q04370

IPRPPFSSH

10.50

-5.84

-3.83

PRPPFSSHS

14.36

-4.03

-2.02

DEDIPRPPF

15.85

-4.92

-2.91

P40450

PPLPESLSM

11.56

-1.84

0.17

PPLPNGLLS

11.63

-3.73

-1.72

PKLFPRLSS

11.71

-4.46

-2.45

P47135

KTPRASPSR

9.33

-0.77

1.24

YFSYPGVFP

10.65

-6.74

-4.73

ASKTPRASP

12.70

-5.06

-3.05

P15274

PKNKPGWVV

11.06

-5.91

-3.90

YPPPPKPSY

13.46

-5.08

-3.07

PPPKPSYNS

13.87

-4.49

-2.48

P53112

SISPNGIPG

13.44

-2.55

-0.54

Q12110

SPVAPSPNH

12.51

-4.38

-2.37

QGSPVAPSP

15.04

-4.82

-2.81

 


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