ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-16.PDB
Scoring matrix: PEX13_1JQQ-16_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.58
Foldx random average score for Saccharomyces cerevisiae: 18.848

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1952136
Proteins after disorder filtering: 4769
 Total fragments: 172823
Proteins after pattern filtering: 2329
 Total fragments: 19839
Proteins after MINT filtering: 7
 Total fragments: 73


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.58

5.74

0.00

Best peptides

YPPIRSEEP

0.00

0.36

-5.38

         
Interactors      
Q04370

DIPRPPFSS

13.37

-2.30

-8.04

EDIPRPPFS

13.74

0.69

-5.05

IPRPPFSSH

16.05

-2.41

-8.15

P40450

SPKLFPRLS

9.60

-4.84

-10.58

LPQLPPPPP

10.83

-8.36

-14.10

HDLVTPPAP

11.48

-0.27

-6.01

P47135

YPGVFPVSG

8.56

-5.35

-11.09

YFSYPGVFP

9.29

0.42

-5.32

KEQCPFPLP

10.97

-1.92

-7.66

P15274

PPPKPSYNS

8.97

-1.76

-7.50

DDQNPKNKP

9.87

-2.57

-8.31

PPPPKPSYN

13.61

-0.98

-6.72

P53112

FSISPNGIP

12.49

-1.63

-7.37

PNGIPGIDT

13.27

3.08

-2.66

SISPNGIPG

18.08

-0.89

-6.63

Q08446

NSSHSPISP

9.46

-0.67

-6.41

Q12110

SPVAPSPNH

13.54

1.88

-3.86

NSQGSPVAP

14.14

0.16

-5.58

QGSPVAPSP

16.27

1.46

-4.28

 


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