ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-15.PDB
Scoring matrix: PEX13_1JQQ-15_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.66
Foldx random average score for Saccharomyces cerevisiae: 13.533

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1360345
Proteins after disorder filtering: 4167
 Total fragments: 46271
Proteins after pattern filtering: 1828
 Total fragments: 6629
Proteins after MINT filtering: 5
 Total fragments: 18


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.66

-0.45

0.00

Best peptides

RWKIIRKKR

0.00

-9.11

-8.66

         
Interactors      
P40450

HDLVTPPAP

11.47

-4.63

-4.18

SSPKLFPRL

12.40

-2.28

-1.83

PPPLPDLFK

12.52

-3.93

-3.48

P47135

KTPRASPSR

9.42

-3.46

-3.01

YPGVFPVSG

11.14

-6.90

-6.45

FPLPPPNVN

11.31

-4.70

-4.25

Q04370

DIPRPPFSS

12.94

-3.44

-2.99

Q12110

PVAPSPNHR

12.99

-3.53

-3.08

P15274

YPPPPKPSY

11.12

-7.14

-6.69

NPKNKPGWV

11.38

-4.50

-4.05

PPPPKPSYN

12.82

-4.09

-3.64

 


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