ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-11.PDB
Scoring matrix: PEX13_1JQQ-11_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.88
Foldx random average score for Saccharomyces cerevisiae: 13.388

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 2494226
Proteins after disorder filtering: 5042
 Total fragments: 203352
Proteins after pattern filtering: 2348
 Total fragments: 18355
Proteins after MINT filtering: 7
 Total fragments: 68


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.88

-1.86

0.00

Best peptides

YDKRRRK

0.00

-5.87

-4.02

         
Interactors      
Q04370

EDIPRPP

8.64

-5.31

-3.45

DIPRPPF

9.61

-5.69

-3.84

P40450

SSPKLFP

8.11

-4.25

-2.40

KLPQLPP

8.15

-5.62

-3.77

PPLPQSL

8.31

-5.82

-3.97

P47135

KTPRASP

7.32

-4.90

-3.05

CPFPLPP

9.00

-5.14

-3.28

LSPGQPL

9.75

-2.60

-0.75

P15274

NPKNKPG

8.34

-4.56

-2.70

PPKPSYN

8.39

-5.23

-3.38

YPPPPKP

8.99

-5.02

-3.16

P53112

PNGIPGI

10.59

-3.17

-1.31

ISPNGIP

13.29

-1.74

0.11

Q08446

HSPISPL

7.01

-4.07

-2.22

SPISPLK

9.91

-4.07

-2.22

Q12110

PVAPSPN

9.16

-3.45

-1.60

GSPVAPS

11.49

-3.42

-1.56

SPVAPSP

12.93

-3.66

-1.81

 


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