ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-9.PDB
Scoring matrix: NBP2_1YN8-9_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.68
Foldx random average score for Saccharomyces cerevisiae: 13.874

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1398471
Proteins after disorder filtering: 4276
 Total fragments: 54635
Proteins after pattern filtering: 2109
 Total fragments: 11651
Proteins after MINT filtering: 7
 Total fragments: 106


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.68

-2.08

0.00

Best peptides

RRFRPFRH

0.00

-7.21

-5.13

         
Interactors      
Q01389

KRSKPLPP

7.74

-6.47

-4.39

RYPQTPSY

9.69

-3.94

-1.86

RPVPPDSS

9.92

-4.72

-2.64

P53933

RRRPPPPP

6.45

-7.78

-5.70

RRPPPPPI

6.74

-7.55

-5.47

RPPPPPIP

6.87

-8.50

-6.42

P53914

VKPLPPKE

8.67

-6.92

-4.84

KNVKPLPP

9.75

-5.96

-3.88

LPPIDPKD

10.55

-5.93

-3.85

P48562

MRQAPKRP

8.81

-5.50

-3.42

QFPRGPMH

9.23

-5.92

-3.84

SPLNPYRP

9.88

-4.41

-2.33

Q03497

FPSKNPLK

8.44

-5.31

-3.23

LPPIPPTK

8.53

-6.65

-4.57

GKFIPSRP

8.64

-7.05

-4.97

P08018

RAPRRPLS

7.18

-8.92

-6.84

RPNVAPHK

9.45

-6.45

-4.37

APRRPLST

10.75

-6.54

-4.46

Q12469

LKPFPRPS

9.87

-5.35

-3.27

HRLAPSAP

11.40

-3.87

-1.79

ELKPFPRP

11.59

-4.51

-2.43

 


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