ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-7.PDB
Scoring matrix: NBP2_1YN8-7_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 14.39
Foldx random average score for Saccharomyces cerevisiae: 10.981

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1312110
Proteins after disorder filtering: 4340
 Total fragments: 52076
Proteins after pattern filtering: 2018
 Total fragments: 11477
Proteins after MINT filtering: 7
 Total fragments: 115


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

14.39

-0.93

0.00

Best peptides

YFRRWYMW

0.00

-4.45

-3.52

         
Interactors      
Q01389

KPLPPQLL

7.50

-4.76

-3.83

YPQTPSYY

7.63

-4.57

-3.64

KRSKPLPP

7.82

-4.87

-3.94

P53933

RRPPPPPI

7.35

-4.70

-3.77

RPPPPPIP

7.39

-4.65

-3.72

RRRPPPPP

7.75

-6.16

-5.23

P53914

VKPLPPKE

6.47

-5.75

-4.82

KPLPPKED

8.71

-3.82

-2.89

KNVKPLPP

8.73

-4.91

-3.98

P48562

QFPRGPMH

6.53

-4.67

-3.74

MRQAPKRP

7.67

-6.04

-5.11

KPPISAPR

8.04

-3.70

-2.77

Q03497

FPSKNPLK

6.91

-5.54

-4.61

QHKPKVKP

7.41

-4.66

-3.73

IPSRPAPK

7.63

-3.16

-2.23

P08018

RAPRRPLS

7.41

-6.51

-5.58

PPPRLPSD

8.88

-4.38

-3.45

QHPTRPNV

8.96

-3.34

-2.41

Q12469

ELKPFPRP

7.61

-5.12

-4.19

PFPRPSDD

8.06

-6.30

-5.37

KPFPRPSD

8.78

-3.29

-2.36

 


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