ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-6.PDB
Scoring matrix: NBP2_1YN8-6_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 16.18
Foldx random average score for Saccharomyces cerevisiae: 19.463

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 2059052
Proteins after disorder filtering: 4652
 Total fragments: 142550
Proteins after pattern filtering: 2321
 Total fragments: 23599
Proteins after MINT filtering: 8
 Total fragments: 206


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

16.18

7.70

0.00

Best peptides

RRRMGRYPPK

0.00

-3.65

-11.35

         
Interactors      
Q01389

PKREAPKPPA

11.15

0.72

-6.98

RRYPQTPSYY

11.84

2.85

-4.85

YPQTPSYYYD

12.16

0.29

-7.41

P53933

RRRPPPPPIP

10.82

-0.73

-8.43

RPPPPPIPST

10.88

-0.13

-7.83

VSYPGNPTSR

11.59

-0.71

-8.41

P53914

AKNVKPLPPK

12.25

2.01

-5.69

KPLPPKEDDE

14.77

0.80

-6.90

VKPLPPKEDD

14.84

0.94

-6.76

P48562

QFPRGPMHPN

5.86

-4.44

-12.14

YHHQGPSPSP

7.70

-2.84

-10.54

FQNIGPAPRP

8.49

-4.01

-11.71

Q03497

TGLPGSPQVS

11.83

-0.58

-8.28

HKQHKPKVKP

12.28

1.72

-5.98

RPAPKPPSSA

12.31

1.22

-6.48

Q12469

RLAPSAPATK

12.60

1.87

-5.83

PHRLAPSAPA

12.85

1.55

-6.15

HRLAPSAPAT

13.39

0.65

-7.05

P25293

PHNTPASVLN

17.54

3.11

-4.59

NAPTPHNTPA

19.21

3.73

-3.97

P08018

RAPRRPLSTQ

11.39

0.57

-7.13

HPTRPNVAPH

12.70

0.01

-7.69

GPPPRLPSDK

14.74

4.13

-3.57

 


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