ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-29.PDB
Scoring matrix: NBP2_1YN8-29_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 16.67
Foldx random average score for Saccharomyces cerevisiae: 12.365

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1466247
Proteins after disorder filtering: 4056
 Total fragments: 52900
Proteins after pattern filtering: 2041
 Total fragments: 11341
Proteins after MINT filtering: 7
 Total fragments: 111


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

16.67

-2.46

0.00

Best peptides

HMPRRYPHRK

0.00

-8.53

-6.07

         
Interactors      
Q01389

RSKPLPPQLL

7.64

-9.65

-7.19

ASPSYPSIFR

8.44

-8.20

-5.74

SKPLPPQLLS

8.60

-9.19

-6.73

P53933

RRPPPPPIPS

7.99

-9.86

-7.40

VAPPPLPNRQ

9.04

-8.24

-5.78

VRTRRRPPPP

9.09

-8.95

-6.49

P53914

NVKPLPPKED

7.46

-7.30

-4.84

AKNVKPLPPK

9.66

-6.28

-3.82

GAKNVKPLPP

11.02

-8.30

-5.84

P48562

LNPYRPHHNM

5.79

-7.83

-5.37

PLNPYRPHHN

6.89

-7.22

-4.76

PKPPISAPRA

7.06

-8.38

-5.92

Q03497

VKKSFPSKNP

7.52

-7.75

-5.29

KPKVKPSKPE

8.20

-8.05

-5.59

FIPSRPAPKP

8.35

-9.45

-6.99

P08018

GPPPRLPSDK

7.56

-9.62

-7.16

RAPRRPLSTQ

7.60

-9.36

-6.90

TQHPTRPNVA

9.23

-7.66

-5.20

Q12469

ELKPFPRPSD

8.32

-7.18

-4.72

KPFPRPSDDD

8.69

-8.64

-6.18

LKPFPRPSDD

11.04

-5.81

-3.35

 


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