ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-27.PDB
Scoring matrix: NBP2_1YN8-27_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 17.09
Foldx random average score for Saccharomyces cerevisiae: 17.100

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1590820
Proteins after disorder filtering: 4685
 Total fragments: 127307
Proteins after pattern filtering: 2271
 Total fragments: 16502
Proteins after MINT filtering: 8
 Total fragments: 157


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

17.09

3.34

0.00

Best peptides

RKRRRRKWR

0.00

-3.09

-6.43

         
Interactors      
Q01389

STPSRPVPP

10.13

-1.34

-4.68

TPSRPVPPD

10.17

-0.34

-3.68

PKREAPKPP

10.42

-1.20

-4.54

P53933

RTRRRPPPP

3.97

-5.06

-8.40

TRRRPPPPP

8.44

-3.70

-7.04

KRVAPPPLP

11.83

-3.86

-7.20

P53914

KNVKPLPPK

11.98

-0.81

-4.15

KPLPPKEDD

15.99

-0.10

-3.44

NVKPLPPKE

16.98

-1.69

-5.03

P48562

FPRGPMHPN

9.45

-3.41

-6.75

IGPAPRPPS

9.89

-3.68

-7.02

SAPRAPYPS

10.58

-0.05

-3.39

Q03497

FIPSRPAPK

8.20

-3.60

-6.94

IPSRPAPKP

8.90

-2.02

-5.36

SRPAPKPPS

11.51

-2.10

-5.44

Q12469

KPFPRPSDD

12.44

-1.06

-4.40

HRLAPSAPA

13.05

-3.72

-7.06

LKPFPRPSD

13.24

0.51

-2.83

P25293

PTPHNTPAS

13.39

0.35

-2.99

TPHNTPASV

16.16

0.80

-2.54

P08018

RAPRRPLST

7.78

-2.68

-6.02

STQHPTRPN

10.43

-3.53

-6.87

APRRPLSTQ

10.83

-1.78

-5.12

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER