ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-26.PDB
Scoring matrix: NBP2_1YN8-26_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.23
Foldx random average score for Saccharomyces cerevisiae: 13.544

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1437505
Proteins after disorder filtering: 4229
 Total fragments: 65201
Proteins after pattern filtering: 2176
 Total fragments: 15612
Proteins after MINT filtering: 8
 Total fragments: 151


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.23

-2.36

0.00

Best peptides

RRRRRRFPR

0.00

-6.56

-4.20

         
Interactors      
Q01389

PSYPSIFRR

7.88

-6.58

-4.22

RSKPLPPQL

8.52

-6.13

-3.77

RTEPSTPSR

9.04

-5.91

-3.55

P53933

RTRRRPPPP

6.44

-6.79

-4.43

RRRPPPPPI

6.65

-6.75

-4.39

TRRRPPPPP

7.61

-6.72

-4.36

P53914

KNVKPLPPK

9.46

-6.26

-3.90

KPLPPKEDD

11.47

-4.09

-1.73

NVKPLPPKE

11.66

-5.30

-2.94

P48562

RQAPKRPDA

8.52

-8.87

-6.51

SAPRAPYPS

9.06

-4.81

-2.45

PLNPYRPHH

9.20

-8.20

-5.84

Q03497

HKPKVKPSK

7.91

-6.88

-4.52

KFIPSRPAP

8.29

-8.31

-5.95

KVKPSKPEA

8.47

-6.73

-4.37

Q12469

LKPFPRPSD

9.13

-7.18

-4.82

ELKPFPRPS

9.84

-6.05

-3.69

RLAPSAPAT

12.23

-4.76

-2.40

P25293

PTPHNTPAS

13.48

-5.23

-2.87

P08018

DGPPPRLPS

7.66

-7.64

-5.28

RAPRRPLST

8.94

-5.54

-3.18

TQHPTRPNV

10.38

-9.16

-6.80

 


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