ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-25.PDB
Scoring matrix: NBP2_1YN8-25_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 14.58
Foldx random average score for Saccharomyces cerevisiae: 14.350

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1521220
Proteins after disorder filtering: 4632
 Total fragments: 104957
Proteins after pattern filtering: 2314
 Total fragments: 19138
Proteins after MINT filtering: 8
 Total fragments: 171


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

14.58

1.86

0.00

Best peptides

HRRPMGMRP

0.00

-7.13

-8.99

         
Interactors      
Q01389

STPSRPVPP

6.76

-3.34

-5.20

PKREAPKPP

7.53

-2.77

-4.63

SRPVPPDSS

7.60

-5.06

-6.92

P53933

TRRRPPPPP

4.58

-4.43

-6.29

RRPPPPPIP

4.61

-7.32

-9.18

KRVAPPPLP

5.28

-3.46

-5.32

P53914

NVKPLPPKE

6.98

-3.68

-5.54

AKNVKPLPP

7.79

-3.46

-5.32

PLPPKEDDE

9.76

-1.74

-3.60

P48562

TMRQAPKRP

5.81

-3.36

-5.22

QFPRGPMHP

6.91

-3.71

-5.57

GGVAKPKKP

7.82

-3.64

-5.50

Q03497

KPKVKPSKP

5.89

-3.63

-5.49

KFIPSRPAP

6.89

-2.90

-4.76

SRPAPKPPS

7.12

-5.42

-7.28

Q12469

ELKPFPRPS

6.80

-2.37

-4.23

PHRLAPSAP

7.71

-0.67

-2.53

KPFPRPSDD

9.47

-2.53

-4.39

P25293

NAPTPHNTP

11.46

0.83

-1.03

APTPHNTPA

12.44

0.45

-1.41

P08018

GPPPRLPSD

9.04

-2.60

-4.46

QHPTRPNVA

9.21

-3.11

-4.97

PRRPLSTQH

9.38

-2.83

-4.69

 


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