ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-19.PDB
Scoring matrix: NBP2_1YN8-19_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.23
Foldx random average score for Saccharomyces cerevisiae: 16.142

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1608230
Proteins after disorder filtering: 4646
 Total fragments: 93646
Proteins after pattern filtering: 2164
 Total fragments: 10762
Proteins after MINT filtering: 8
 Total fragments: 93


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.23

-1.96

0.00

Best peptides

MRSKTGHKI

0.00

-0.88

1.08

         
Interactors      
Q01389

KRSKPLPPQ

10.22

-5.90

-3.94

IASPTSPKS

10.64

-3.72

-1.76

IPSPSSSPP

10.67

-3.40

-1.44

P53933

PPIPSTQKP

11.25

-4.36

-2.40

PPLPNRQLP

13.86

-5.57

-3.61

PPPLPNRQL

14.70

-4.71

-2.75

P53914

KNVKPLPPK

11.53

-5.33

-3.37

KPLPPKEDD

13.36

-3.54

-1.58

PIDPKDGGR

15.43

-3.84

-1.88

P48562

NPYRPHHNM

9.54

-4.78

-2.82

PRGPMHPNN

10.99

-5.23

-3.27

MRQAPKRPD

11.77

-3.76

-1.80

Q03497

IPSRPAPKP

9.43

-5.47

-3.51

KPSKPEAKS

9.52

-4.37

-2.41

KQHKPKVKP

10.35

-7.20

-5.24

Q12469

APSAPATKN

12.25

-1.60

0.36

RLAPSAPAT

13.20

-4.27

-2.31

HRLAPSAPA

14.65

-3.62

-1.66

P25293

APTPHNTPA

14.57

-2.44

-0.48

P08018

PRLPSDKFS

10.84

-4.00

-2.04

TQHPTRPNV

11.82

-4.72

-2.76

PRRPLSTQH

12.82

-2.39

-0.43

 


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