ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-18.PDB
Scoring matrix: NBP2_1YN8-18_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 17.08
Foldx random average score for Saccharomyces cerevisiae: 16.712

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1600578
Proteins after disorder filtering: 4592
 Total fragments: 109408
Proteins after pattern filtering: 2234
 Total fragments: 15737
Proteins after MINT filtering: 8
 Total fragments: 141


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

17.08

0.46

0.00

Best peptides

RPPIPPRHQY

0.00

6.31

5.85

         
Interactors      
Q01389

RYPQTPSYYY

8.25

-1.95

-2.40

YPQTPSYYYD

9.13

-2.95

-3.41

SPSYPSIFRR

9.44

-0.06

-0.52

P53933

APPPLPNRQL

8.98

-2.50

-2.96

RPPPPPIPST

9.44

-1.28

-1.74

PPPPIPSTQK

12.25

-1.40

-1.86

P53914

LPPIDPKDGG

8.62

-4.31

-4.76

VKPLPPKEDD

10.28

-2.59

-3.04

AKNVKPLPPK

14.55

-0.96

-1.42

P48562

LNPYRPHHNM

7.84

-4.01

-4.46

SPLNPYRPHH

9.76

0.39

-0.07

KPPISAPRAP

10.94

-5.71

-6.17

Q03497

LPPIPPTKSK

5.00

-5.36

-5.82

FPSKNPLKNS

7.44

-5.51

-5.96

KPSKPEAKSK

8.78

-4.15

-4.61

Q12469

ELKPFPRPSD

11.91

-0.07

-0.53

LKPFPRPSDD

12.38

-0.88

-1.34

RPHRLAPSAP

12.61

-4.04

-4.50

P25293

NAPTPHNTPA

15.59

-0.40

-0.85

APTPHNTPAS

16.32

-1.06

-1.52

P08018

PPRLPSDKFS

9.56

-3.67

-4.13

APRRPLSTQH

10.06

-1.94

-2.40

HPTRPNVAPH

10.59

-2.61

-3.06

 


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