ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-17.PDB
Scoring matrix: NBP2_1YN8-17_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.54
Foldx random average score for Saccharomyces cerevisiae: 15.009

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1524282
Proteins after disorder filtering: 4592
 Total fragments: 77450
Proteins after pattern filtering: 2103
 Total fragments: 9020
Proteins after MINT filtering: 8
 Total fragments: 81


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.54

-0.35

0.00

Best peptides

RRYMRGHKL

0.00

-7.84

-7.49

         
Interactors      
Q01389

RRYPQTPSY

7.26

-5.91

-5.56

RPVPPDSSY

8.00

-6.84

-6.49

YPQTPSYYY

10.47

-3.65

-3.30

P53933

PPPPPIPST

11.94

-2.65

-2.30

PPLPNRQLP

13.67

-3.65

-3.30

PPPLPNRQL

14.02

-4.53

-4.18

P53914

KPLPPKEDD

13.03

-2.23

-1.88

KNVKPLPPK

13.80

-2.89

-2.54

PIDPKDGGR

14.39

-1.38

-1.03

P48562

NPYRPHHNM

9.47

-5.90

-5.55

YSKQPQSPL

10.84

-4.06

-3.71

MRQAPKRPD

11.74

-3.28

-2.93

Q03497

KPSKPEAKS

10.00

-5.00

-4.65

IPSRPAPKP

11.23

-6.52

-6.17

PIPPTKSKT

11.58

-1.91

-1.56

Q12469

LKPFPRPSD

11.62

-3.14

-2.79

RLAPSAPAT

11.65

-2.45

-2.10

APSAPATKN

13.05

-2.24

-1.89

P25293

PTPHNTPAS

12.95

0.13

0.48

P08018

GPPPRLPSD

11.57

-2.33

-1.98

PRLPSDKFS

12.81

-1.34

-0.99

APRRPLSTQ

12.86

-1.38

-1.03

 


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