ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-14.PDB
Scoring matrix: NBP2_1YN8-14_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.25
Foldx random average score for Saccharomyces cerevisiae: 14.695

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1377196
Proteins after disorder filtering: 4004
 Total fragments: 39392
Proteins after pattern filtering: 1714
 Total fragments: 5574
Proteins after MINT filtering: 8
 Total fragments: 66


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

18.25

-0.08

0.00

Best peptides

RWKRRRWWR

0.00

-5.07

-4.99

         
Interactors      
Q01389

RYPQTPSYY

10.44

-1.17

-1.09

KRSKPLPPQ

11.71

-5.30

-5.22

SPSYPSIFR

12.04

-2.60

-2.52

P53933

PPPIPSTQK

12.02

-3.03

-2.95

APPPLPNRQ

13.45

-1.50

-1.42

RPPPPPIPS

14.07

-5.50

-5.42

P53914

LPPIDPKDG

11.89

-3.86

-3.78

KNVKPLPPK

12.91

-4.24

-4.16

KPLPPKEDD

14.21

-0.11

-0.03

P48562

KPPISAPRA

10.68

-4.41

-4.33

RQAPKRPDA

11.25

-3.09

-3.01

NPYRPHHNM

11.59

-8.11

-8.03

Q03497

HKPKVKPSK

9.95

-3.30

-3.22

LPPIPPTKS

11.13

-4.73

-4.65

FPSKNPLKN

11.57

-2.94

-2.86

Q12469

LKPFPRPSD

12.41

-0.08

0.00

RLAPSAPAT

14.35

-0.83

-0.75

PFPRPSDDD

14.41

-1.65

-1.57

P25293

TPHNTPASV

13.80

0.00

0.08

P08018

RAPRRPLST

9.35

-4.27

-4.19

APRRPLSTQ

10.59

-5.73

-5.65

PPPRLPSDK

11.20

-4.96

-4.88

 


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