ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-12.PDB
Scoring matrix: NBP2_1YN8-12_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 9.72
Foldx random average score for Saccharomyces cerevisiae: 7.407

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1350843
Proteins after disorder filtering: 4455
 Total fragments: 63967
Proteins after pattern filtering: 2178
 Total fragments: 12823
Proteins after MINT filtering: 7
 Total fragments: 131


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

9.72

-0.86

0.00

Best peptides

RWWFRMMR

0.00

-3.51

-2.65

         
Interactors      
Q01389

PSYPSIFR

4.13

-2.41

-1.55

SSPPPIPK

4.34

-2.65

-1.79

RSKPLPPQ

4.91

-3.27

-2.41

P53933

RRRPPPPP

4.31

-3.85

-2.99

VAPPPLPN

4.54

-3.90

-3.04

RRPPPPPI

4.56

-3.35

-2.49

P53914

KNVKPLPP

4.25

-4.14

-3.28

NVKPLPPK

5.15

-2.72

-1.86

KPLPPKED

5.46

-3.58

-2.72

P48562

VAKPKKPA

4.30

-2.73

-1.87

IGPAPRPP

4.87

-3.14

-2.28

RQAPKRPD

5.18

-3.18

-2.32

Q03497

KVKPSKPE

3.79

-3.14

-2.28

KSFPSKNP

4.09

-2.95

-2.09

HKPKVKPS

4.66

-3.25

-2.39

P08018

DGPPPRLP

4.30

-2.74

-1.88

TQHPTRPN

5.08

-3.03

-2.17

GPPPRLPS

5.44

-3.64

-2.78

Q12469

LKPFPRPS

3.32

-3.14

-2.28

ELKPFPRP

5.47

-2.95

-2.09

KPFPRPSD

6.01

-3.03

-2.17

 


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