ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-9.PDB
Scoring matrix: NBP2_1SEM-9_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 19.23
Foldx random average score for Saccharomyces cerevisiae: 14.429

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1303716
Proteins after disorder filtering: 4246
 Total fragments: 49815
Proteins after pattern filtering: 1987
 Total fragments: 9481
Proteins after MINT filtering: 7
 Total fragments: 93


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

19.23

-2.90

0.00

Best peptides

RRPRPPFY

0.00

-13.15

-10.25

         
Interactors      
Q01389

KRSKPLPP

8.72

-7.62

-4.71

YPQTPSYY

9.06

-8.19

-5.29

TPSRPVPP

9.95

-8.88

-5.98

P53933

TRRRPPPP

7.06

-9.63

-6.73

RRRPPPPP

8.43

-9.00

-6.10

RRPPPPPI

8.48

-9.20

-6.29

P53914

VKPLPPKE

10.29

-8.08

-5.18

KNVKPLPP

11.38

-7.13

-4.22

LPPIDPKD

11.45

-6.32

-3.42

P48562

NPYRPHHN

8.96

-11.12

-8.21

MRQAPKRP

9.36

-6.95

-4.04

QFPRGPMH

9.87

-9.46

-6.56

Q03497

IPSRPAPK

8.85

-11.12

-8.21

FPSKNPLK

10.02

-7.49

-4.59

LPPIPPTK

10.11

-8.41

-5.51

P08018

RAPRRPLS

7.13

-10.62

-7.71

HPTRPNVA

7.48

-10.98

-8.08

APRRPLST

9.62

-8.49

-5.59

Q12469

HRLAPSAP

10.78

-5.38

-2.48

PFPRPSDD

11.31

-9.37

-6.46

LKPFPRPS

11.48

-6.39

-3.48

 


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