ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-7.PDB
Scoring matrix: NBP2_1SEM-7_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 15.34
Foldx random average score for Saccharomyces cerevisiae: 12.274

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1359660
Proteins after disorder filtering: 4356
 Total fragments: 55983
Proteins after pattern filtering: 1973
 Total fragments: 10275
Proteins after MINT filtering: 7
 Total fragments: 126


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

15.34

-3.05

0.00

Best peptides

KRRRPPWW

0.00

-11.04

-7.99

         
Interactors      
Q01389

KRSKPLPP

7.28

-7.05

-4.00

KPLPPQLL

9.10

-6.85

-3.80

KREAPKPP

9.15

-6.17

-3.12

P53933

TRRRPPPP

6.36

-6.43

-3.38

RRPPPPPI

6.96

-6.90

-3.85

RRRPPPPP

7.12

-7.28

-4.23

P53914

VKPLPPKE

7.72

-7.68

-4.63

KPLPPKED

10.53

-5.78

-2.73

KNVKPLPP

10.64

-6.41

-3.36

P48562

MRQAPKRP

8.19

-6.61

-3.56

QFPRGPMH

8.68

-6.57

-3.52

NPYRPHHN

9.44

-8.52

-5.47

Q03497

IPSRPAPK

8.29

-4.83

-1.78

FPSKNPLK

8.87

-5.05

-2.00

HKPKVKPS

9.35

-5.27

-2.22

P08018

RAPRRPLS

7.73

-10.25

-7.20

PRLPSDKF

8.94

-4.66

-1.61

PRRPLSTQ

8.96

-4.66

-1.61

Q12469

ELKPFPRP

9.51

-4.87

-1.82

HRLAPSAP

10.78

-5.43

-2.38

PFPRPSDD

10.83

-9.35

-6.30

 


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