ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-5.PDB
Scoring matrix: NBP2_1SEM-5_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.02
Foldx random average score for Saccharomyces cerevisiae: 17.471

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1862543
Proteins after disorder filtering: 4550
 Total fragments: 103100
Proteins after pattern filtering: 2319
 Total fragments: 21621
Proteins after MINT filtering: 8
 Total fragments: 185


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.02

1.24

0.00

Best peptides

LLFRPPRRHF

0.00

-8.96

-10.20

         
Interactors      
Q01389

KRSKPLPPQL

8.60

-2.72

-3.96

TKSASPPASP

10.35

-1.88

-3.12

PSSSPPPIPK

10.66

-1.28

-2.52

P53933

TRRRPPPPPI

6.65

-5.13

-6.37

RRRPPPPPIP

8.26

-7.89

-9.13

RVAPPPLPNR

9.10

-7.30

-8.54

P53914

AKNVKPLPPK

10.29

-2.20

-3.44

KNVKPLPPKE

11.42

-1.38

-2.62

LPPIDPKDGG

11.52

-3.55

-4.79

P48562

PQRTAPKPPI

8.22

-4.44

-5.68

TAPKPPISAP

8.35

-4.37

-5.61

YHHQGPSPSP

9.03

-2.83

-4.07

Q03497

FIPSRPAPKP

8.96

-4.18

-5.42

HKQHKPKVKP

9.45

-2.48

-3.72

EQPLPPIPPT

9.92

-3.63

-4.87

Q12469

ELKPFPRPSD

10.64

-3.31

-4.55

RLAPSAPATK

12.00

-3.98

-5.22

LAPSAPATKN

12.90

-3.14

-4.38

P25293

DNAPTPHNTP

13.19

-1.05

-2.29

TPHNTPASVL

14.36

-4.38

-5.62

PHNTPASVLN

15.03

-2.49

-3.73

P08018

IVDGPPPRLP

7.27

-4.50

-5.74

PLSTQHPTRP

10.20

-4.10

-5.34

PPPRLPSDKF

10.42

-6.69

-7.93

 


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