ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-29.PDB
Scoring matrix: NBP2_1SEM-29_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.91
Foldx random average score for Saccharomyces cerevisiae: 14.120

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1320911
Proteins after disorder filtering: 3825
 Total fragments: 39551
Proteins after pattern filtering: 1895
 Total fragments: 9548
Proteins after MINT filtering: 7
 Total fragments: 90


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.91

-2.44

0.00

Best peptides

HYRFRPPRWH

0.00

-15.02

-12.58

         
Interactors      
Q01389

RSKPLPPQLL

8.18

-8.24

-5.80

RYPQTPSYYY

8.80

-9.84

-7.40

ASPSYPSIFR

9.93

-8.55

-6.12

P53933

APPPLPNRQL

8.88

-9.12

-6.68

RRPPPPPIPS

10.22

-10.32

-7.88

RTRRRPPPPP

10.57

-11.30

-8.87

P53914

NVKPLPPKED

8.75

-9.33

-6.89

AKNVKPLPPK

9.94

-8.17

-5.73

PLPPKEDDEL

12.46

-6.06

-3.62

P48562

PYRPHHNMIN

8.56

-10.58

-8.14

LNPYRPHHNM

9.27

-9.83

-7.39

TMRQAPKRPD

9.57

-9.21

-6.78

Q03497

NGKFIPSRPA

7.52

-9.11

-6.67

KPKVKPSKPE

8.40

-8.44

-6.00

HKQHKPKVKP

9.12

-8.75

-6.31

P08018

PRRPLSTQHP

10.49

-10.33

-7.89

TQHPTRPNVA

11.03

-6.65

-4.21

QHPTRPNVAP

11.61

-10.42

-7.98

Q12469

ELKPFPRPSD

9.53

-8.87

-6.43

KPFPRPSDDD

12.39

-8.41

-5.97

PHRLAPSAPA

13.61

-7.63

-5.20

 


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